Human influenza virus infections

C Peteranderl, S Herold… - Seminars in respiratory …, 2016 - thieme-connect.com
Seasonal and pandemic influenza are the two faces of respiratory infections caused by
influenza viruses in humans. As seasonal influenza occurs on an annual basis, the …

NS1: a Key protein in the “game” between influenza A virus and host in innate immunity

Z Ji, X Wang, X Liu - Frontiers in cellular and infection microbiology, 2021 - frontiersin.org
Since the influenza pandemic occurred in 1918, people have recognized the perniciousness
of this virus. It can cause mild to severe infections in animals and humans worldwide, with …

Viral determinants of influenza A virus host range

AV Cauldwell, JS Long… - Journal of General …, 2014 - microbiologyresearch.org
Typical avian influenza A viruses are restricted from replicating efficiently and causing
disease in humans. However, an avian virus can become adapted to humans by mutating or …

Research progress on the nonstructural protein 1 (NS1) of influenza a virus

X Zhang, Y Zhang, F Wei - Virulence, 2024 - Taylor & Francis
Influenza A virus (IAV) is the leading cause of highly contagious respiratory infections, which
poses a serious threat to public health. The non-structural protein 1 (NS1) is encoded by …

Altering cell death pathways as an approach to cure HIV infection

AD Badley, A Sainski, F Wightman, SR Lewin - Cell death & disease, 2013 - nature.com
Recent cases of successful control of human immunodeficiency virus (HIV) by bone marrow
transplant in combination with suppressive antiretroviral therapy (ART) and very early …

The contribution of viral proteins to the synergy of Influenza and bacterial co-infection

M Mikušová, K Tomčíková, K Briestenská… - Viruses, 2022 - mdpi.com
A severe course of acute respiratory disease caused by influenza A virus (IAV) infection is
often linked with subsequent bacterial superinfection, which is difficult to cure. Thus …

[HTML][HTML] The novel H7N9 influenza A virus NS1 induces p53-mediated apoptosis of A549 cells

Y Yan, Y Du, G Wang, Y Deng, R Li, K Li - Cellular Physiology and …, 2016 - karger.com
Background: H7N9, emerged as an avian influenza virus outbreak in Eastern China in early
2013, and represented another major threat to global health. Roles of its NS1 protein, an …

Infection of chicken bone marrow mononuclear cells with subgroup J avian leukosis virus inhibits dendritic cell differentiation and alters cytokine expression

D Liu, Q Qiu, X Zhang, M Dai, J Qin, J Hao… - Infection, genetics and …, 2016 - Elsevier
Subgroup J avian leukosis virus (ALV-J) is an oncogenic retrovirus known to induce tumor
formation and immunosuppression in infected chickens. One of the organs susceptible to …

Influenza A virus NS1 protein‐induced JNK activation and apoptosis are not functionally linked

W Nacken, V Wixler, C Ehrhardt… - Cellular …, 2017 - Wiley Online Library
Expression of the influenza A virus (IAV) nonstructural protein (NS1) results in the activation
of c‐Jun N‐terminal kinase (JNK). Both NS1 and JNK are involved in apoptosis induction. To …

Highly pathogenic avian influenza A virus H5N1 non‑structural protein 1 is associated with apoptotic activation of the intrinsic mitochondrial pathway

Q Bian, J Lu, L Zhang, Y Chi… - Experimental and …, 2017 - spandidos-publications.com
Outbreaks of avian influenza A (H5N1) virus infection have significant health and economic
consequences. Non‑structural protein 1 (NS1) is an essential virulence factor of the highly …