The complex bidirectional communication between the gut and the brain is finely
orchestrated by different systems, including the endocrine, immune, autonomic, and enteric …

Currently, there is no disease-modifying treatment available for Alzheimer's and Parkinson's
disease (AD and PD) and that includes the highly controversial approval of the Aβ-targeting …

Activation of microglia by classical inflammatory mediators can convert astrocytes into a
neurotoxic A1 phenotype in a variety of neurological diseases,. Development of agents that …

Abstract Insulin-like growth factor-1 (IGF-1), a pleiotropic polypeptide, plays an essential role
in CNS development and maturation. Glucagon-like peptide-1 (GLP-1) is an endogenous …

Depression has emerged as a major cause of mortality globally. Many studies have reported
risk factors and mechanisms associated with depression, but it is as yet unclear how these …

Depression is a common neuropsychiatric disorder characterized by persistent depressed
mood and causes serious socioeconomic burden worldwide. Hyperactivity of the …

Readily available nutrient-rich foods exploit our inherent drive to overconsume, creating an
environment of overnutrition. This transformative setting has led to persistent health issues …

Naeem K, Tariq Al Kury L, Nasar F, et al. J Inflamm Res. 2021; 14: 1313–1329. At the
authors request, the Editor and Publisher of Journal of Inflammation Research wish to retract …

Depression is a highly prevalent mood disorder and one of the major health concerns in
modern society. Moreover, it is characterized by a high prevalence of coexistence with many …

Diabetes increases the likelihood of developing depression and vice versa. Research on
this bidirectional association has somewhat managed to delineate the interplay among …