[HTML][HTML] Exploring the 175-year history of spirometry and the vital lessons it can teach us today

A Kouri, RJ Dandurand, OS Usmani… - European Respiratory …, 2021 - Eur Respiratory Soc
175 years have elapsed since John Hutchinson introduced the world to his version of an
apparatus that had been in development for nearly two centuries, the spirometer. Though he …

Bronchiolitis obliterans syndrome after lung or haematopoietic stem cell transplantation: current management and future directions

AR Glanville, C Benden, A Bergeron… - ERJ open …, 2022 - Eur Respiratory Soc
Bronchiolitis obliterans syndrome (BOS) may develop after either lung or haematopoietic
stem cell transplantation (HSCT), with similarities in histopathological features and clinical …

Chronic lung allograft dysfunction: Definition, diagnostic criteria, and approaches to treatment―A consensus report from the Pulmonary Council of the ISHLT

GM Verleden, AR Glanville, ED Lease… - The Journal of Heart …, 2019 - jhltonline.org
The outcomes of transplantation vary widely by organ. Lung transplantation (LTx) has rather
poor long-term outcome, with a current median post-transplant survival of 6.0 years. 1, 2 …

[HTML][HTML] National institutes of health consensus development project on criteria for clinical trials in chronic graft-versus-Host disease: IV. the 2020 highly morbid forms …

D Wolff, V Radojcic, R Lafyatis, R Cinar… - … and cellular therapy, 2021 - Elsevier
Chronic graft-versus-host disease (GVHD) can be associated with significant morbidity, in
part because of nonreversible fibrosis, which impacts physical functioning (eye, skin, lung …

Risk assessment of chronic lung allograft dysfunction phenotypes: validation and proposed refinement of the 2019 International Society for Heart and Lung …

L Levy, E Huszti, B Renaud-Picard, G Berra… - The Journal of Heart and …, 2020 - Elsevier
BACKGROUND Chronic lung allograft dysfunction (CLAD) is a heterogeneous condition.
Characterization of CLAD phenotypes is essential to enhance the understanding of …

Lung transplantation for COPD/pulmonary emphysema

GM Verleden, J Gottlieb - European Respiratory Review, 2023 - Eur Respiratory Soc
COPD and α-1 antitrypsin deficiency emphysema remain one of the major indications for
lung transplantation. If all other treatment possibilities are exhausted or not possible …

Donor-derived, cell-free DNA levels by next-generation targeted sequencing are elevated in allograft rejection after lung transplantation

KK Khush, I De Vlaminck, H Luikart… - ERJ Open …, 2021 - Eur Respiratory Soc
Surveillance after lung transplantation is critical to the detection of acute cellular rejection
(ACR) and prevention of chronic lung allograft dysfunction (CLAD). Therefore, we measured …

Immune processes in the pathogenesis of chronic lung allograft dysfunction: identifying the missing pieces of the puzzle

S Bos, L Milross, AJ Filby, R Vos… - European Respiratory …, 2022 - Eur Respiratory Soc
Lung transplantation is the optimal treatment for selected patients with end-stage chronic
lung diseases. However, chronic lung allograft dysfunction remains the leading obstacle to …

Effector immune cells in chronic lung allograft dysfunction: A systematic review

S Bos, AJ Filby, R Vos, AJ Fisher - Immunology, 2022 - Wiley Online Library
Chronic lung allograft dysfunction (CLAD) remains the major barrier to long‐term survival
after lung transplantation and improved insight into its underlying immunological …

[HTML][HTML] Plasma donor-derived cell-free DNA levels are increased during acute cellular rejection after lung transplant: pilot data

D Sayah, SS Weigt, A Ramsey, A Ardehali… - Transplantation …, 2020 - journals.lww.com
Background. Telehealth platforms with remote phlebotomy and biomarker implementation
represent a novel paradigm for surveillance after lung transplantation (LT). In a pilot study …