The human growth hormone gene (GH1) and the insulin-like growth factor 1 and 2 genes
(IGF1 and IGF2) encode the central elements of a key pathway influencing growth in …

Intercellular communication within an organism, between populations, or across species
and kingdoms forms the basis of many ecosystems in which organisms coexist through …

Many complex diseases exhibit pronounced sex differences that can affect both the initial
risk of developing the disease, as well as clinical disease symptoms, molecular …

Growth hormone is fundamental for growth during childhood and for maintaining bone mass
and homeostasis in the adults. GH deficiency causes decreased bone growth and …

Background Hormones are signaling molecules that play vital roles in various life processes,
like growth and differentiation, physiology, and reproduction. These molecules are mostly …

Background In multicellular organisms, an intercellular signaling network communicates
information from the environment or distant tissues to defined target cells. Intercellular …

Bioinformatics has delivered great contributions to genome and genomics research, without
which the world-wide success of this and other global ('omics') approaches would not have …

Biological objects exhibit emergent properties that are not readily explainable by the
features of their constituent parts: A system is more than just a sum of different elements. In …

Dementia is the progressive decline in cognitive function due to damage or disease in the
body beyond what might be expected from normal aging. Based on neuropathological and …

The HumanPSD database on the complete proteomes of human, mouse and rat has been
integrated with the databases TRANSFAC on gene regulation and TRANSPATH on signal …