Alzheimer's disease (AD) is a neurodegenerative disease with significant socioeconomic
burden worldwide. Although genetics and environmental factors play a role, AD is highly …

The spectrum of information related to precision medicine in diabetes generally includes
clinical data, genetics, and omics-based biomarkers that can guide personalized decisions …

Spinal cord injury (SCI) is an extreme neurological impairment with few effective drug
treatments. Pyroptosis is a recently found and proven type of programmed cell death that is …

Pharmaceutical compounds are among several classes of contaminants of emerging
concern, such as pesticides, heavy metals and personal care products, all of which are a …

Introduction Despite the ability of cancer cells to survive glucose deprivation, most studies
on anti-cancer effect of metformin explored its impact on glucose metabolism. No study ever …

As a vision-threatening complication of diabetes mellitus (DM), proliferative diabetic
retinopathy (PDR) is associated with sustained metabolic disorders. Herein, we collected the …

Preparations of the roots, stems, and leaves of Rhinachantus nasutus (L.) Kurz (RNK) have
been used empirically in traditional medicine to treat diabetes, eczema, pulmonary …

Obesity, type 2 diabetes (T2D), and severe coronavirus disease 2019 (COVID-19) are
closely associated. The aim of this study was to elucidate the casual and mediating …

Pharmacometabolomics in early phase clinical trials demonstrate the metabolic profiles of a
subject responding to a drug treatment in a controlled environment, whereas …

Metformin is widely used for treating type 2 diabetes mellitus (T2D). However, the efficacy of
metformin monotherapy is highly variable within the human population. Understanding the …