Enveloped viruses encompass some of the most common human pathogens causing
infections of different severity, ranging from no or very few symptoms to lethal disease as …

Hepatitis C virus (HCV) envelope glycoprotein heterodimer, E1E2, plays an essential role in
virus entry and assembly. Furthermore, due to their exposure at the surface of the virion …

Hepatitis C virus (HCV) is a major cause of liver disease and hepatocellular carcinoma
worldwide. HCV establishes a chronic infection in the majority of cases. However, some …

The envelope proteins of hepatitis B virus (HBV) bear an N-linked glycosylation site at N146
within the immunodominant a-determinant in the antigenic loop (AGL) region. This …

Despite 20 years of research, a vaccine to prevent hepatitis C virus (HCV) infection has not
been developed. A vaccine to prevent HCV will need to induce broadly reactive immunity …

Hepatitis C virus (HCV) requires multiple receptors for its attachment to and entry into cells.
Our previous studies found that human syndecan-1 (SDC-1), SDC-2, and T cell …

The majority of individuals exposed to hepatitis C virus (HCV) establish a persistent
infection, which is a leading cause of chronic liver disease, cirrhosis and hepatocellular …

Chronic viral hepatitis infections are a major public health concern, with an estimated 290
million individuals infected with hepatitis B virus (HBV) globally. This virus has been a …

Hepatitis C virus (HCV) is a major health problem worldwide. Early detection of the infection
will help better management of the infected cases. The monoclonal antibodies (mAb) of mice …

In the 26 years since the discovery of Hepatitis C virus (HCV) a major global research effort
has illuminated many aspects of the viral life cycle, facilitating the development of targeted …