2. INTRODUCTION The investigation of many fundamental processes in life sciences
requires straightforward tools for fast, sensitive, reliable, and reproducible detection of …

Fluorescence spectroscopy, one of the most informative and sensitive analytical techniques,
has played and continues to play key roles in modern research. Indeed, unraveling the inner …

During the last ten years, the use of molecular markers, revealing polymorphism at the DNA
level, has been playing an increasing part in animal genetics studies. Amongst others, the …

Understanding the relationship between genetic variation and biological function on a
genomic scale is expected to provide fundamental new insights into the biology, evolution …

Molecular analysis of predation, through polymerase chain reaction amplification of prey
remains within the faeces or digestive systems of predators, is a rapidly growing field …

Oligonucleotide probe arrays have enabled massively parallel analysis of gene expression
levels from a single cDNA sample. Application of microarray technology to analyzing …

There is an increasing interest in single nucleotide polymorphism (SNP) typing in the
forensic field, not only for the usefulness of SNPs for defining Y chromosome or mtDNA …

DNA pooling is a practical way to reduce the cost of large-scale association studies to
identify susceptibility loci for common diseases. Pooling allows allele frequencies in groups …

Scanners for conventional microarrays typically have imaging spot sizes in the range of 3–5
microns, insufficient to resolve the~ 5-micron-spaced features on the randomly assembled …

One of the fruits of the Human Genome Project is the discovery of millions of DNA sequence
variants in the human genome. The majority of these variants are single nucleotide …