Predicting the risk of post-hepatectomy portal hypertension using a digital twin: A clinical proof of concept
Background & Aims Despite improvements in medical and surgical techniques, post-
hepatectomy liver failure (PHLF) remains the leading cause of postoperative death. High …
hepatectomy liver failure (PHLF) remains the leading cause of postoperative death. High …
Organ‐PAM: photoacoustic microscopy of whole‐organ multiset vessel systems
J Zhang, D Peng, W Qin, W Qi, X Liu… - Laser & Photonics …, 2023 - Wiley Online Library
Organs maintain their unique functions through a variety of distinctive vessel systems.
However, examination of multiset vessels over the entire organ still remains challenging due …
However, examination of multiset vessels over the entire organ still remains challenging due …
Global sensitivity analysis of hepatic venous pressure gradient (HVPG) measurement with a stochastic computational model of the hepatic circulation
Hepatic venous pressure gradient (HVPG) is a widely employed surrogate of portal pressure
gradient (PPG) in the diagnosis of portal hypertension (PHT). However, little is known about …
gradient (PPG) in the diagnosis of portal hypertension (PHT). However, little is known about …
Anatomically based simulation of hepatic perfusion in the human liver
Liver structures of a healthy subject are digitised and segmented from computed
tomography (CT) images, and hepatic perfusion is modelled in the hepatic artery and portal …
tomography (CT) images, and hepatic perfusion is modelled in the hepatic artery and portal …
[HTML][HTML] Multiscale reconstruction of various vessels in the intact murine liver lobe
The liver contains a variety of vessels and participates in miscellaneous physiological
functions. While past studies generally focused on certain hepatic vessels, we …
functions. While past studies generally focused on certain hepatic vessels, we …
Model Assisted Analysis of the Hepatic Arterial Buffer Response During Ex Vivo Porcine Liver Perfusion
Objective: The hepatic arterial buffer response is a well-known phenomenon in hepatic
circulation, describing the response of hepatic arterial resistance to changes in portal vein …
circulation, describing the response of hepatic arterial resistance to changes in portal vein …
[HTML][HTML] Influences of anatomorphological features of the portal venous system on postsplenectomy hemodynamic characteristics in patients with portal hypertension …
Splenectomy, as an effective surgery for relieving complications caused by portal
hypertension, is often accompanied by a significantly increased incidence of postoperative …
hypertension, is often accompanied by a significantly increased incidence of postoperative …
[HTML][HTML] Examining temporal changes in model-optimized parameters using longitudinal hemodynamic measurements
Background We previously applied hemodynamic data to personalize a mathematical model
of the circulation expressed as physically interpretable parameters. The aim of this study …
of the circulation expressed as physically interpretable parameters. The aim of this study …
A computational model-based study on the exchangeability of hepatic venous pressure gradients measured in multiple hepatic veins
Hepatic venous pressure gradient (HVPG) is a hemodynamic index widely used for
evaluating the severity of portal hypertension. Theoretically, HVPG can be measured in any …
evaluating the severity of portal hypertension. Theoretically, HVPG can be measured in any …
Predicting the risk of postsplenectomy thrombosis in patients with portal hypertension using computational hemodynamics models: a proof-of-concept study
Background The high incidence of thrombosis in the portal venous system following
splenectomy (a frequently adopted surgery for treating portal hypertension in patients with …
splenectomy (a frequently adopted surgery for treating portal hypertension in patients with …