Repeated, episodic bouts of skeletal muscle contraction undertaken frequently as structured
exercise training are a potent stimulus for physiological adaptation in many organs …

Autophagy refers to the formation of autophagosomes by membrane wrapping part of the
cytoplasm and the organelles and proteins that need to be degraded in the cells …

Skeletal muscle possesses a remarkable ability to adapt to various physiologic conditions.
AMPK is a sensor of intracellular energy status that maintains energy stores by fine-tuning …

Moderately trained male subjects (mean age 25 years; range 19–33 years) completed an 8‐
week exercise training intervention consisting of continuous moderate cycling at 157±20 W …

This review summarizes how fatty acid (FA) oxidation is regulated in skeletal muscle during
exercise. From the available evidence it seems that acetyl-CoA availability in the …

Chronic kidney disease (CKD) is prevalent in 9.1% of the global population and is a
significant public health problem associated with increased morbidity and mortality. CKD is …

Skeletal muscle is a tissue with a low mitochondrial content under basal conditions, but it is
responsive to acute increases in contractile activity patterns (ie exercise) which initiate the …

During the course of life, muscle mass undergoes many changes in terms of quantity and
quality. Skeletal muscle is a dynamic tissue able to hypertrophy or atrophy according to …

Background Parkin is a ubiquitin ligase that is involved in the selective removal of
dysfunctional mitochondria. This process is termed mitophagy and can assist in …

Autophagy is an evolutionarily conserved lysosomal degradation pathway that maintains
metabolism and homeostasis by eliminating protein aggregates and damaged organelles …