Hydrogel scaffolds for tissue engineering: the importance of polymer choice

CD Spicer - Polymer Chemistry, 2020 - pubs.rsc.org
Hydrogel scaffolds that can repair or regrow damaged biological tissue have great potential
for the treatment of injury and disease. These biomaterials are widely used in the tissue …

Covalently Crosslinked hydrogels via step‐growth reactions: crosslinking chemistries, polymers, and clinical impact

Y Gao, K Peng, S Mitragotri - Advanced Materials, 2021 - Wiley Online Library
Hydrogels are an important class of biomaterials with the unique property of high‐water
content in a crosslinked polymer network. In particular, chemically crosslinked hydrogels …

Biodegradable thermoresponsive polymers: Applications in drug delivery and tissue engineering

KJ Hogan, AG Mikos - Polymer, 2020 - Elsevier
Thermoresponsive polymers have been investigated for a variety of clinical applications
which make use of in situ gelation at physiological temperatures. However, for biomedical …

Review of applications and future prospects of stimuli-responsive hydrogel based on thermo-responsive biopolymers in drug delivery systems

S Chatterjee, PC Hui - Polymers, 2021 - mdpi.com
Some of thermo-responsive polysaccharides, namely, cellulose, xyloglucan, and chitosan,
and protein-like gelatin or elastin-like polypeptides can exhibit temperature dependent sol …

Polysaccharide and polypeptide based injectable thermo-sensitive hydrogels for local biomedical applications

HF Darge, AT Andrgie, HC Tsai, JY Lai - International journal of biological …, 2019 - Elsevier
Injectable thermo-responsive hydrogels have been studied for various biomedical
applications including; drug delivery, cell encapsulation, and tissue repairing. There are …

3D bioprinting of methylcellulose/gelatin-methacryloyl (MC/GelMA) bioink with high shape integrity

H Rastin, RT Ormsby, GJ Atkins… - ACS Applied Bio …, 2020 - ACS Publications
The advent of three-dimensional (3D) bioprinting offers a feasible approach to construct
complex structures suitable for tissue regeneration, during which cell-laden materials are …

Thermo-responsive methylcellulose hydrogels: From design to applications as smart biomaterials

L Bonetti, L De Nardo, S Farè - Tissue Engineering Part B: Reviews, 2021 - liebertpub.com
Methylcellulose (MC) is an attractive material used to produce thermo-responsive hydrogels.
They undergo sol-gel transition when a critical temperature is reached, thus modifying their …

Hydrogels as potential nano-, micro-and macro-scale systems for controlled drug delivery

A Chyzy, M Tomczykowa, ME Plonska-Brzezinska - Materials, 2020 - mdpi.com
This review is an extensive evaluation and essential analysis of the design and formation of
hydrogels (HGs) for drug delivery. We review the fundamental principles of HGs (their …

Methylcellulose–a versatile printing material that enables biofabrication of tissue equivalents with high shape fidelity

T Ahlfeld, V Guduric, S Duin, AR Akkineni… - Biomaterials …, 2020 - pubs.rsc.org
With the aid of biofabrication, cells can be spatially arranged in three dimensions, which
offers the opportunity to guide tissue maturation in a better way compared to traditional …

Three-dimensional printing of chemically crosslinked gelatin hydrogels for adipose tissue engineering

NC Negrini, N Celikkin, P Tarsini, S Farè… - …, 2020 - iopscience.iop.org
Despite their outstanding potential and the success that has already been achieved with
three-dimensional (3D) printed hydrogel scaffolds, there has been little investigation into …