Piper species are aromatic plants used as spices in the kitchen, but their secondary
metabolites have also shown biological effects on human health. These plants are rich in …

Glutathione transferase classical GSH conjugation activity plays a critical role in cellular
detoxification against xenobiotics and noxious compounds as well as against oxidative …

The use of synthetic, natural, or biological agents to minimize the occurrence of cancer in
healthy individuals is defined as cancer chemoprevention. Chemopreventive agents inhibit …

The ethnomedical uses of Piper (胡椒Hú Jiāo) plants as anticancer agents, in vitro cytotoxic
activity of both extracts and compounds from Piper plants, and in vivo antitumor activity and …

Pancreatic cancer is the world's fourth largest causative factor of mortality with a five year of
survival rate. Poor definitive diagnosis can be ascribed to both problematic early detections …

Colorectal cancer (CRC) represents the third most commonly diagnosed cancer and the
second leading cause of cancer death worldwide. The modern concept of cancer biology …

Antimicrobial natural preparations involving cinnamon, storax and propolis have been long
used topically for treating infections. Cinnamic acids and related molecules are partly …

Epithelial-to-mesenchymal transition (EMT) is a self-regulated physiological process
required for tissue repair that, in non-controled conditions may lead to fibrosis …

Accumulating evidence indicates that senescent cells play an important role in many age-
associated diseases. The pharmacological depletion of senescent cells (SCs) with a …

Endemic in 149 tropical and subtropical countries, neglected tropical diseases (NTDs) affect
more than 1 billion people annually, including 875 million children in developing …