Malaria immunity in man and mosquito: insights into unsolved mysteries of a deadly infectious disease
PD Crompton, J Moebius, S Portugal… - Annual review of …, 2014 - annualreviews.org
Malaria is a mosquito-borne disease caused by parasites of the obligate intracellular
Apicomplexa phylum the most deadly of which, Plasmodium falciparum, prevails in Africa …
Apicomplexa phylum the most deadly of which, Plasmodium falciparum, prevails in Africa …
Neurological complications of malaria
S Trivedi, A Chakravarty - Current neurology and neuroscience reports, 2022 - Springer
Abstract Purpose of Review To discuss the neurological complications and pathophysiology
of organ damage following malaria infection. Recent Findings The principal advancement …
of organ damage following malaria infection. Recent Findings The principal advancement …
Respiratory manifestations of malaria
Respiratory distress develops in up to 25% of adults and 40% of children with severe
falciparum malaria. Its diverse causes include respiratory compensation of metabolic …
falciparum malaria. Its diverse causes include respiratory compensation of metabolic …
Pathogenesis, clinical features, and neurological outcome of cerebral malaria
Cerebral malaria is the most severe neurological complication of Plasmodium falciparum
malaria. Even though this type of malaria is most common in children living in sub-Saharan …
malaria. Even though this type of malaria is most common in children living in sub-Saharan …
Serum levels of the proinflammatory cytokines interleukin-1 beta (IL-1β), IL-6, IL-8, IL-10, tumor necrosis factor alpha, and IL-12 (p70) in Malian children with severe …
KE Lyke, R Burges, Y Cissoko, L Sangare… - Infection and …, 2004 - Am Soc Microbiol
Inflammatory cytokines play an important role in human immune responses to malarial
disease. However, the role of these mediators in disease pathogenesis, and the relationship …
disease. However, the role of these mediators in disease pathogenesis, and the relationship …
Cytokines: accelerators and brakes in the pathogenesis of cerebral malaria
Cerebral malaria (CM) is a major life-threatening complication of Plasmodium falciparum
infection. The nature of the pathogenetic processes leading to the cerebral complications is …
infection. The nature of the pathogenetic processes leading to the cerebral complications is …
The war between the malaria parasite and the immune system: immunity, immunoregulation and immunopathology
K Artavanis-Tsakonas, JE Tongren… - Clinical & Experimental …, 2003 - academic.oup.com
Throughout history malaria has proved to be a significant threat to human health. Between
300 and 500 million clinical cases occur each year worldwide, approximately 2 million of …
300 and 500 million clinical cases occur each year worldwide, approximately 2 million of …
Clinical features and pathogenesis of severe malaria
A major change in recent years has been the recognition that severe malaria, predominantly
caused by Plasmodium falciparum, is a complex multi-system disorder presenting with a …
caused by Plasmodium falciparum, is a complex multi-system disorder presenting with a …
The role of IL-10 in malaria: a double edged sword
IL-10 produced by CD4+ T cells suppresses inflammation by inhibiting T cell functions and
the upstream activities of antigen presenting cells (APCs). IL-10 was first identified in Th2 …
the upstream activities of antigen presenting cells (APCs). IL-10 was first identified in Th2 …
Severe Plasmodium vivax malaria exhibits marked inflammatory imbalance
BB Andrade, A Reis-Filho, SM Souza-Neto, J Clarêncio… - Malaria journal, 2010 - Springer
Background Despite clinical descriptions of severe vivax malaria cases having been
reported, data regarding immunological and inflammatory patterns are scarce. In this report …
reported, data regarding immunological and inflammatory patterns are scarce. In this report …