Mammalian oocytes and early embryos derived from in vitro production are highly
susceptible to a variety of cellular stresses. During oocyte maturation and preimplantation …

One in three cancer deaths worldwide are caused by gastric and colorectal cancer
malignancies. Although the incidence and fatality rates differ significantly from country to …

Reactive oxygen species (ROS) is one of the most common causatives of male infertility. At
normal physiological levels, ROS mediate essential physiological roles to ensure proper …

As the best adapted high altitude population, Tibetans feature a relatively high offspring
survival rate. Genome-wide studies have identified hundreds of candidate SNPs related to …

Bisphenol A (BPA) is an environmental contaminant widely used in the plastic industry. BPA
has been demonstrated to be an endocrine disruptor and has an adverse effect on the …

Blast injuries include the various types of internal and external trauma caused by the impact
force of high-speed blast waves with multiple mechanisms involved. Thoracic blast exposure …

Acrylamide (ACR) is an important chemical raw material for wastewater treatment, paper
industry and textile industry, which is widely exposed from occupational, environmental and …

Abstract Aflatoxin B1 (AFB1) is a type of mycotoxin produced by the fungi Aspergillus flavus
and Aspergillus parasiticus. AFB1 is considered as the most toxic mycotoxin owing to its …

Abstract Connexin 43 (CX43) is a component of gap junctions. The lack of functional CX43
induces oxidative stress, autophagy, and apoptosis in somatic cells. However, the role of …

Ischemia/reperfusion is a major cause of acute kidney injury and can induce apoptosis in
renal epithelial tubule (HK-2) cells. Accumulating evidence indicates that endoplasmic …