A unified analysis of evolutionary and population constraint in protein domains highlights structural features and pathogenic sites
Protein evolution is constrained by structure and function, creating patterns in residue
conservation that are routinely exploited to predict structure and other features. Similar …
conservation that are routinely exploited to predict structure and other features. Similar …
Comparative evaluation of methods for the prediction of protein–ligand binding sites
The accurate identification of protein–ligand binding sites is of critical importance in
understanding and modulating protein function. Accordingly, ligand binding site prediction …
understanding and modulating protein function. Accordingly, ligand binding site prediction …