Psilocybin is increasingly studied for its antidepressant effect, but its optimal dosage for
depression remains unclear. We conducted a systematic review and a dose-response meta …

Hallucinogenic mushrooms have been used in religious and cultural ceremonies for
centuries. Of late, psilocybin, the psychoactive compound in hallucinogenic mushrooms, has …

Psilocybin is being investigated as a treatment in adults with treatment-resistant depression
(TRD). Withdrawal from serotonergic antidepressant drugs is a common prerequisite for …

Importance Bipolar II disorder (BDII) is a debilitating condition frequently associated with
difficult-to-treat depressive episodes. Psilocybin has evidence for rapid-acting …

Previous studies have investigated challenging, difficult, or distressing classic psychedelic
experiences, but little is known about the prevalence and associations of such experiences …

Background: Growing numbers of people are using psychedelics for personal
psychotherapy outside clinical settings, but research on such use is scarce. Aims: This study …

Psilocybin is being investigated as a potential treatment for psychiatric and neurological
disorders. Only a few studies have evaluated the pharmacokinetics (PKs) of psilocybin and …

Background: Research on psilocybin has become increasingly popular during the current
psychedelic renaissance, which began in the early 1990s. Psilocybin's effects on mental …

Introduction Psychedelic drugs were used quite extensively before their prohibition in 1968
which delayed research. However, since the 1990s, studies on the potential therapeutic …

Depression is a common mental health issue that affects 280 million people in the world with
a high mortality rate, as well as being a leading cause of disability. Psychopharmacological …