Acute respiratory distress syndrome in adults: diagnosis, outcomes, long-term sequelae, and management

EA Gorman, CM O'Kane, DF McAuley - The Lancet, 2022 - thelancet.com
Acute respiratory distress syndrome (ARDS) is characterised by acute hypoxaemic
respiratory failure with bilateral infiltrates on chest imaging, which is not fully explained by …

Therapeutic advances in COVID-19

N Murakami, R Hayden, T Hills, H Al-Samkari… - Nature Reviews …, 2023 - nature.com
Over 2 years have passed since the start of the COVID-19 pandemic, which has claimed
millions of lives. Unlike the early days of the pandemic, when management decisions were …

ESICM guidelines on acute respiratory distress syndrome: definition, phenotyping and respiratory support strategies

G Grasselli, CS Calfee, L Camporota, D Poole… - Intensive care …, 2023 - Springer
The aim of these guidelines is to update the 2017 clinical practice guideline (CPG) of the
European Society of Intensive Care Medicine (ESICM). The scope of this CPG is limited to …

Strategies to prevent ventilator-associated pneumonia, ventilator-associated events, and nonventilator hospital-acquired pneumonia in acute-care hospitals: 2022 …

M Klompas, R Branson, K Cawcutt, M Crist… - Infection Control & …, 2022 - cambridge.org
The purpose of this document is to highlight practical recommendations to assist acute care
hospitals to prioritize and implement strategies to prevent ventilator-associated pneumonia …

Awake prone positioning for non-intubated patients with COVID-19-related acute hypoxaemic respiratory failure: a systematic review and meta-analysis

J Li, J Luo, I Pavlov, Y Perez, W Tan, O Roca… - The Lancet …, 2022 - thelancet.com
Background Awake prone positioning has been broadly utilised for non-intubated patients
with COVID-19-related acute hypoxaemic respiratory failure, but the results from published …

Factors for success of awake prone positioning in patients with COVID-19-induced acute hypoxemic respiratory failure: analysis of a randomized controlled trial

M Ibarra-Estrada, J Li, I Pavlov, Y Perez, O Roca… - Critical Care, 2022 - Springer
Background Awake prone positioning (APP) improves oxygenation in coronavirus disease
(COVID-19) patients and, when successful, may decrease the risk of intubation. However …

Assessment of awake prone positioning in hospitalized adults with COVID-19: a nonrandomized controlled trial

ET Qian, CL Gatto, O Amusina, ML Dear… - JAMA internal …, 2022 - jamanetwork.com
Importance Awake prone positioning may improve hypoxemia among patients with COVID-
19, but whether it is associated with improved clinical outcomes remains unknown. Objective …

[HTML][HTML] Physiotherapy management for COVID-19 in the acute hospital setting and beyond: an update to clinical practice recommendations

P Thomas, C Baldwin, L Beach, B Bissett, I Boden… - Journal of …, 2022 - Elsevier
This document provides an update to the recommendations for physiotherapy management
for adults with coronavirus disease 2019 (COVID-19) in the acute hospital setting. It …

Randomised clinical trials in critical care: past, present and future

A Granholm, W Alhazzani, LPG Derde, DC Angus… - Intensive care …, 2022 - Springer
Randomised clinical trials (RCTs) are the gold standard for providing unbiased evidence of
intervention effects. Here, we provide an overview of the history of RCTs and discuss the …

Effect of awake prone positioning on endotracheal intubation in patients with COVID-19 and acute respiratory failure: a randomized clinical trial

W Alhazzani, KKS Parhar, J Weatherald, Z Al Duhailib… - Jama, 2022 - jamanetwork.com
Importance The efficacy and safety of prone positioning is unclear in nonintubated patients
with acute hypoxemia and COVID-19. Objective To evaluate the efficacy and adverse events …