Nrf2: a dark horse in Alzheimer's disease treatment

A Osama, J Zhang, J Yao, X Yao, J Fang - Ageing research reviews, 2020 - Elsevier
Abstract Alzheimer's disease (AD), an age-dependent neurodegenerative disorder, is the
main cause of dementia. Common hallmarks of AD include the amyloid β-peptide (Aβ) …

Bioactive polysaccharides from seaweeds

F Hentati, L Tounsi, D Djomdi, G Pierre, C Delattre… - Molecules, 2020 - mdpi.com
Bioactive compounds with diverse chemical structures play a significant role in disease
prevention and maintenance of physiological functions. Due to the increase in industrial …

Nutritional composition and biological properties of sixteen edible mushroom species

M Dimopoulou, A Kolonas, S Mourtakos… - Applied Sciences, 2022 - mdpi.com
Mushrooms are considered to be functional foods with high nutritional, culinary, and
pharmacological values, and there has been an increase in their consumption, both through …

Transcription factor NRF2 as a promising therapeutic target for Alzheimer's disease

Z Qu, J Sun, W Zhang, J Yu, C Zhuang - Free Radical Biology and …, 2020 - Elsevier
Oxidative stress is considered as one of the pathogenesis of Alzheimer's disease (AD) and
plays an important role in the occurrence and development of AD. Nuclear factor erythroid 2 …

Biopharmaceutical applications of microbial polysaccharides as materials: a review

Y Song, S Li, H Gong, RCS Yip, H Chen - International Journal of Biological …, 2023 - Elsevier
Biological characteristics of natural polymers make microbial polysaccharides an excellent
choice for biopharmaceuticals. Due to its easy purifying procedure and high production …

[HTML][HTML] Therapeutic applications of mushrooms and their biomolecules along with a glimpse of in silico approach in neurodegenerative diseases

SN Rai, D Mishra, P Singh, E Vamanu… - Biomedicine & …, 2021 - Elsevier
Neurodegenerative diseases (NDs) represent a common neurological pathology that
determines a progressive deterioration of the brain or the nervous system. For treating NDs …

Advances in polysaccharides of natural source of the anti-Alzheimer's disease effect and mechanism

Z Zhang, S Wang, H Tan, P Yang, Y Li, L Xu… - Carbohydrate …, 2022 - Elsevier
Alzheimer's disease (AD) is a complex neurodegenerative disorder. The pathology is
characterized by the generation of amyloid plaques and neuronal fiber tangles in the brain …

The interaction between mushroom polysaccharides and gut microbiota and their effect on human health: A review

J Zhao, Y Hu, C Qian, M Hussain, S Liu, A Zhang, R He… - Biology, 2023 - mdpi.com
Simple Summary A growing number of studies have shown that mushroom polysaccharides
could exert anti-diabetes, anti-intestinal inflammation and antitumor effects by regulating gut …

[HTML][HTML] Gut microbiota and its metabolites: bridge of dietary nutrients and Alzheimer's disease

G Zhu, J Zhao, H Zhang, G Wang, W Chen - Advances in Nutrition, 2023 - Elsevier
Alzheimer's disease (AD) is a neurodegenerative disease characterized by progressive
cognitive impairment and neuroinflammation. Recent research has revealed the crucial role …

Attenuation of Nrf2/Keap1/ARE in Alzheimer's disease by plant secondary metabolites: A mechanistic review

S Fakhri, M Pesce, A Patruno, SZ Moradi, A Iranpanah… - Molecules, 2020 - mdpi.com
Alzheimer's disease (AD) is a progressive neuronal/cognitional dysfunction, leading to
disability and death. Despite advances in revealing the pathophysiological mechanisms …