Intrinsically disordered protein regions exist in a collection of dynamic interconverting
conformations that lack a stable 3D structure. These regions are structurally heterogeneous …

Intrinsically disordered proteins and protein regions (IDRs) are abundant in eukaryotic
proteomes and play a wide variety of essential roles. Instead of folding into a stable …

Phosphorylation and dephosphorylation of proteins by kinases and phosphatases are
central to cellular responses and function. The structural effects of serine and threonine …

Despite significant advances in the understanding of cancer biology, cancer is still a leading
cause of death worldwide. Expression of the tumor microenvironment component …

Osteopontin (OPN) is a multifunctional protein found in all vertebrates. OPN is expressed in
many different cell types, and is consequently found in most tissues and physiological …

Osteopontin (OPN) is a bone-derived phosphoglycoprotein related to physiological and
pathological mechanisms that nowadays has gained relevance due to its role in the immune …

Simple Summary Osteopontin (OPN) is a protein produced by immune cells, as well as
many other cell types including tumor cells, that is highly modified with sugars and …

In recent biomedical research, bioinformatics and computational analyses have played
essential roles for examining experimental findings and database information. Several …

Chondroitin sulfate (CS) is a ubiquitous glycosaminoglycan covalently attached to the core
proteins of cell surface, extracellular, and intracellular proteoglycans. The multistep and …

A variety of species could be detected by using nanopores engineered with various
recognition sites based upon non-covalent interactions, including electrostatic, aromatic …