The leading cause of heart disease in developed countries is coronary atherosclerosis,
which is not simply a result of ageing but a chronic inflammatory process that can lead to …

Acute ischemic stroke (AIS) is the most common type of stroke and requires immediate
reperfusion. Current acute reperfusion therapies comprise the administration of intravenous …

New findings unravel novel mechanotransduction pathways and effector functions in
platelets, establishing mechanobiology as a pivotal component of platelet function. These …

Thrombocytopenia caused by long-term radiotherapy and chemotherapy exists in cancer
treatment. Previous research demonstrates that 5-Hydroxtrayptamine (5-HT) and its …

Background How platelets interact with and influence the tumor microenvironment (TME)
remains poorly characterized. Methods We compared the presence and participation of …

BACKGROUND: Platelets play an important role in cardiovascular and cerebrovascular
diseases. Abdominal aortic aneurysm (AAA) is a highly lethal, atherosclerosis-related …

Testing the hemocompatibility of medical devices after their interaction with blood entails the
need to evaluate the activation of blood elements and the degree of their coagulation and …

Objectives Thrombocytopenia is a disease in which the number of platelets in the peripheral
blood decreases. It can be caused by multiple genetic factors, and numerous challenges are …

Adrenaline has recently been found to trigger phosphatidylserine (PS) exposure on blood
platelets, resulting in amplification of the coagulation process, but the mechanism is only …

Glanzmann thrombasthenia (GT) is the most common inherited platelet disorder (IPD) with
mucocutaneous bleeding and a failure of platelets to aggregate when stimulated. The …