[HTML][HTML] Drug treatments in Alzheimer's disease
Despite the significant public health issue that it poses, only five medical treatments have
been approved for Alzheimer's disease (AD) and these act to control symptoms rather than …
been approved for Alzheimer's disease (AD) and these act to control symptoms rather than …
Current and future treatments in Alzheimer's disease
A Atri - Seminars in neurology, 2019 - thieme-connect.com
The foundation of current Alzheimer's disease (AD) treatment involves pharmacological and
nonpharmacological management and care planning predicated on patient-centered …
nonpharmacological management and care planning predicated on patient-centered …
[HTML][HTML] X-linked ubiquitin-specific peptidase 11 increases tauopathy vulnerability in women
Although women experience significantly higher tau burden and increased risk for
Alzheimer's disease (AD) than men, the underlying mechanism for this vulnerability has not …
Alzheimer's disease (AD) than men, the underlying mechanism for this vulnerability has not …
Therapeutics of Alzheimer's disease: Past, present and future
Alzheimer's disease (AD) is the most common cause of dementia worldwide. The etiology is
multifactorial, and pathophysiology of the disease is complex. Data indicate an exponential …
multifactorial, and pathophysiology of the disease is complex. Data indicate an exponential …
The biology and pathobiology of glutamatergic, cholinergic, and dopaminergic signaling in the aging brain
A Gasiorowska, M Wydrych, P Drapich… - Frontiers in aging …, 2021 - frontiersin.org
The elderly population is growing worldwide, with important health and socioeconomic
implications. Clinical and experimental studies on aging have uncovered numerous …
implications. Clinical and experimental studies on aging have uncovered numerous …
Therapeutics of neurotransmitters in Alzheimer's disease
R Kandimalla, PH Reddy - Journal of Alzheimer's Disease, 2017 - content.iospress.com
Alzheimer's disease (AD) is a progressive neurodegenerative disease, characterized by the
loss of memory, multiple cognitive impairments and changes in the personality and …
loss of memory, multiple cognitive impairments and changes in the personality and …
Advancements in the development of multi-target directed ligands for the treatment of Alzheimer's disease
Alzheimer's disease (AD) is a multifactorial irreversible neurological disorder which results
in cognitive impairment, loss of cholinergic neurons in synapses of the basal forebrain and …
in cognitive impairment, loss of cholinergic neurons in synapses of the basal forebrain and …
The Alzheimer's disease clinical spectrum: diagnosis and management
A Atri - Medical Clinics, 2019 - medical.theclinics.com
Alzheimer's disease (AD) is the most common cause of cognitive impairment or dementia in
individuals older than 65 years and, with rising longevity, a worldwide pandemic of mild …
individuals older than 65 years and, with rising longevity, a worldwide pandemic of mild …
Memantine and cholinesterase inhibitors: complementary mechanisms in the treatment of Alzheimer's disease
CG Parsons, W Danysz, A Dekundy, I Pulte - Neurotoxicity research, 2013 - Springer
This review describes the preclinical mechanisms that may underlie the increased
therapeutic benefit of combination therapy—with the N-methyl-d-aspartate receptor …
therapeutic benefit of combination therapy—with the N-methyl-d-aspartate receptor …
Pharmacotherapy evolution in Alzheimer's disease: current framework and relevant directions
Alzheimer's disease (AD), once considered a rare disease, is now the most common form of
dementia in the elderly population. Current drugs (cholinesterase inhibitors and glutamate …
dementia in the elderly population. Current drugs (cholinesterase inhibitors and glutamate …