Comet assay: an essential tool in toxicological research
M Glei, T Schneider, W Schlörmann - Archives of toxicology, 2016 - Springer
The comet assay is a versatile, reliable, cost-efficient, and fast technique for detecting DNA
damage and repair in any tissue. It is useable in almost any cell type and applicable to both …
damage and repair in any tissue. It is useable in almost any cell type and applicable to both …
3-MCPD as contaminant in processed foods: State of knowledge and remaining challenges
A Eisenreich, BH Monien, ME Götz, T Buhrke… - Food Chemistry, 2023 - Elsevier
Chloro-1, 2-propanediol (3-MCPD) and its fatty acid esters (FE) are present as contaminants
in different processed foods. Based on the available toxicological data the potential risk of 3 …
in different processed foods. Based on the available toxicological data the potential risk of 3 …
Gut homeostasis and microbiota under attack: Impact of the different types of food contaminants on gut health
Food contaminants represent food constituents that are accidentally introduced during food
preparation cycle. In addition to their direct toxic effects on human health at different levels …
preparation cycle. In addition to their direct toxic effects on human health at different levels …
Exposure assessment of process-related contaminants in food by biomarker monitoring
IMCM Rietjens, P Dussort, H Günther, P Hanlon… - Archives of …, 2018 - Springer
Exposure assessment is a fundamental part of the risk assessment paradigm, but can often
present a number of challenges and uncertainties. This is especially the case for process …
present a number of challenges and uncertainties. This is especially the case for process …
Toxicity of Dietary Exposure to 3‐Monochloropropanediol, Glycidol, and Their Fatty Acid Esters
3‐Monochloropropane‐1, 2‐diol (3‐MCPD), 2, 3‐epoxy‐1‐propanol (glycidol), and their
fatty acid esters are heat‐induced food toxicants that have widely been investigated. This …
fatty acid esters are heat‐induced food toxicants that have widely been investigated. This …
Evaluation of an in vitro three-dimensional HepaRG spheroid model for genotoxicity testing using the high-throughput CometChip platform
Three-dimensional (3D) culture systems are increasingly being used for genotoxicity studies
due to improved cell-to-cell interactions and tissue-like structures that are limited or lacking …
due to improved cell-to-cell interactions and tissue-like structures that are limited or lacking …
In vitro toxicological assessment of free 3-MCPD and select 3-MCPD esters on human proximal tubule HK-2 cells
ME Mossoba, MST Mapa, M Araujo, Y Zhao… - Cell Biology and …, 2020 - Springer
Chloropropanols are chemical contaminants that can be formed during industrial processing
of foods, such as lipids used in commercially available infant and toddler formula in the USA …
of foods, such as lipids used in commercially available infant and toddler formula in the USA …
[HTML][HTML] Assessment of intestinal absorption/metabolism of 3-chloro-1, 2-propanediol (3-MCPD) and three 3-MCPD monoesters by Caco-2 cells
M Araujo, JK Beekman, MST Mapa, S MacMahon… - Toxicology in vitro, 2020 - Elsevier
chloro-1, 2-propanediol (3-MCPD) and 3-MCPD esters are contaminants present in a variety
of processed foods, including infant formulas. Toxicological data are unavailable in humans …
of processed foods, including infant formulas. Toxicological data are unavailable in humans …
[PDF][PDF] 同位素内标-气相色谱-质谱法测定婴幼儿配方乳粉中缩水甘油脂肪酸酯的含量
胡守江, 周静, 张妮, 周耀斌, 赵艳菊, 叶青 - 理化检验-化学分册, 2018 - qikan.cmes.org
将奶粉样品(4.000 0 g) 的氨性乙醇溶液用乙醚(25, 15, 15 mL) 和石油醚(25, 15, 15 mL) 先后3
次提取其脂肪; 合并上层液相, 蒸发除去溶剂后于(100±2)℃ 烘干, 于4℃ 保存 …
次提取其脂肪; 合并上层液相, 蒸发除去溶剂后于(100±2)℃ 烘干, 于4℃ 保存 …
DNA Damage Estimation after Chronic and Combined Exposure to Endocrine Disruptors: An In Vivo Real-Life Risk Simulation Approach
Exposure to chemical substances has always been a matter of concern for the scientific
community. During the last few years, researchers have been focusing on studying the …
community. During the last few years, researchers have been focusing on studying the …