Risk of relapse is a major challenge in the treatment of substance use disorders. Several
types of learning and memory mechanisms are involved in substance use and have …

Highlights•Goal-directed and habitual modes of behavioral control can be behaviorally
dissociated.•Recent work reveals distinct contributions of striatal cell populations to goal …

The present article provides a historical review of the place and response learning plus-
maze tasks with a focus on the behavioral and neurobiological findings. The article begins …

Behavioral flexibility allows individuals to adapt to situations in which rewards and goals
change. The dorsolateral striatum (DLS) is part of corticostriatal circuits that is involved in …

High levels of emotional arousal can impair spatial memory mediated by the hippocampus,
and enhance stimulus-response (SR) habit memory mediated by the dorsolateral striatum …

The present experiments investigated the involvement of N-methyl-d-aspartate (NMDA)
receptors of the dorsolateral striatum (DLS) in consolidation of extinction in a habit memory …

The present review describes a role for the dorsal striatum in extinction. Evidence from brain
lesion and pharmacological studies indicate that the dorsolateral region of the striatum …

The inability to learn an adaptive coping strategy in a novel stressful condition leads to
dysfunctional stress coping, a marker of mental disturbances. This study tested the …

Dopamine (DA) signaling dysfunction is believed to contribute to multiple neuropsychiatric
disorders including attention-deficit/hyperactivity disorder (ADHD). The rare DA transporter …

The view that different kinds of memory are mediated by dissociable neural systems has
received extensive experimental support. Dissociations between memory systems are …