Iron overload can be the result of either dysregulated iron metabolism in the case of
hereditary hemochromatosis or repeated blood transfusions in the case of secondary …

Background and objective A deficit in zinc has been related to a higher probability of
developing cardiovascular diseases (CVDs). The anti-inflammatory and anti-oxidative …

Background: β-Thalassemia major, the most common inherited anemia in the world, is
associated with imbalance in the oxidant-antioxidant system. The objective of this study was …

Oxidative stress is a contributing factor to many chronic diseases. It has been investigated
that zinc (Zn) may enhance the antioxidant defense. The current dose-response and time …

ABSTRACT Introduction: Silibinin (silybin), a non-toxic natural polyphenolic flavonoid, is the
principal and the most biologically active component of silymarin. It is efficient in the …

Background Haemoglobinopathies, inherited disorders of haemoglobin synthesis
(thalassaemia) or structure (sickle cell disease), are responsible for significant morbidity and …

Background: Patients with β-thalassemia major (BTM) had variable prevalence of
undernutrition and abnormal body composition. Methods: We performed an electronic …

Background Iron overload‐induced oxidative stress and transfusion‐acquired hepatitis C
virus (HCV) infection are the main reasons of liver damage in beta thalassemia major (β …

Thalassemia and the blood transfusion complications associated with it predispose children
to poor bone health. This study was conducted to determine the prevalence of bone-related …

Abstract β-Thalassemia (β-thal) is a type of hereditary anemia affecting hemoglobin (Hb)
synthesis causing severe chronic anemia in homozygous patients. Regular blood …