Interoception refers to the representation of the internal states of an organism, and includes
the processes by which it senses, interprets, integrates, and regulates signals from within …

Alcohol is a major contributor to global disease and a leading cause of preventable death,
causing approximately 88,000 deaths annually in the United States alone. Alcohol use …

Interoceptive pathways may be manipulated at various levels to develop interventions to
improve symptoms in a range of disorders. Primarily through the lens of the respiratory …

Growing evidence indicates that the glucagon-like peptide-1 (GLP-1) system is involved in
the neurobiology of addictive behaviors, and GLP-1 analogues may be used for the …

Over the past two decades, whole food supplementation strategies have been leveraged to
target mental health. In addition, there has been increasing attention on the ability of gut …

Our gut harbours trillions of microorganisms essential for the maintenance of homeostasis
and host physiology in health and disease. In the last decade, there has been a growing …

Ghrelin is a peptide that is produced by endocrine cells that are primarily localized in the
stomach. Ghrelin receptors (GHSR) are expressed in the brain and periphery. Preclinical …

Since the mid 1980's, the impact of gastrointestinal (GI) microbiome changes during alcohol
use disorder has been an area of significant interest. This work has resulted in the …

Discovered as a peptide involved in releasing growth hormone, ghrelin was initially
characterized as the “hunger hormone.” However, emerging research indicates that ghrelin …

Alcohol use disorder (AUD) has been associated with impairments in social and emotional
cognition that play a crucial role in the development and maintenance of addiction …