Genome editing and bioinformatics

K Nakamae, H Bono - Gene and Genome Editing, 2022 - Elsevier
Bioinformatics has become an indispensable technology in molecular biology for genome
editing. In this review, we outline various bioinformatic techniques necessary for genome …

BMP-9 mediates fibroproliferation in fibrodysplasia ossificans progressiva through TGF-β signaling

C Zhao, Y Inada, S Motoike, D Kamiya… - EMBO Molecular …, 2024 - embopress.org
Fibrodysplasia ossificans progressiva (FOP) is a rare genetic disorder presenting with
progressive heterotopic ossification (HO) in soft tissues. Early-stage FOP is characterized by …

Monocarboxylate transporter 4 deficiency enhances high‐intensity interval training‐induced metabolic adaptations in skeletal muscle

Y Tamura, E Jee, K Kouzaki, T Kotani… - The Journal of …, 2024 - Wiley Online Library
High‐intensity exercise stimulates glycolysis, subsequently leading to elevated lactate
production within skeletal muscle. While lactate produced within the muscle is …

Effects of blastocyst elongation and implantation chamber formation on the alignment of the embryonic axis and uterine axis in mice

J Sakurai, S Oka, Y Higuchi, S Ohsawa… - Frontiers in Cell and …, 2024 - frontiersin.org
Embryo implantation involves a series of events that bring the embryo and maternal tissues
into contact to support post-implantation development in mammals. During implantation …

[HTML][HTML] KOnezumi-AID: Automation Software for Efficient Multiplex Gene Knockout Using Target-AID

T Taki, K Morimoto, S Mizuno, A Kuno - International Journal of Molecular …, 2024 - mdpi.com
With the groundbreaking advancements in genome editing technologies, particularly
CRISPR-Cas9, creating knockout mutants has become highly efficient. However, the …

[PDF][PDF] Baymiev An. Kh., Gubaydullin IM, Baymiev Al. Kh., Chemeris AV Some novelties in CRISPR/Cas genome editing and related areas

BR Kuluev, OY Kiryanova, GA Gerashchenkov… - 2019 - researchgate.net
The ongoing research on CRISPR/Cas loci is so diverse, that can be called no fewer than
“The CRISPR/Cas World” or even “The CRISPR/Cas Universe”. This review covers only a …

Некоторые новшества в CRISPR/Cas геномном редактировании и в смежных областях

БР Кулуев, ОЮ Кирьянова, ГА Геращенков… - Биомика, 2019 - elibrary.ru
Проводимые исследования, так или иначе связанные с CRISPR/Cas-локусами,
настолько разнообразны, что все что вокруг них делается впору называть" Мир …

KOnezumi-AID: A Software to Automate the Design of Multiplex Knockouts Using Target-AID

T Taki, K Morimoto, S Mizuno, A Kuno - bioRxiv, 2024 - biorxiv.org
With the groundbreaking advancements in genome editing technologies, particularly
CRISPR-Cas9, creating knockout mutants has become highly efficient. However, the …

[HTML][HTML] Strategies of genome editing design for gene knockout

S Mizuno, H Suzuki - 2023 - europepmc.org
Genome editing technology has enabled us to flexibly modify endogenous genes (1, 2). Due
to its versatility, this technology has been applied to gene therapy, lineage analysis, gene …

[HTML][HTML] Strategies of genome editing design for gene knockout

FG Gel, PCRE Kit, FGDTR Kit - europepmc.org
Genome editing technology has enabled us to flexibly modify endogenous genes (1, 2). Due
to its versatility, this technology has been applied to gene therapy, lineage analysis, gene …