[HTML][HTML] QSAR, simulation techniques, and ADMET/pharmacokinetics assessment of a set of compounds that target MAO-B as anti-Alzheimer agent

A Ajala, A Uzairu, GA Shallangwa… - Future Journal of …, 2023 - Springer
Background Alzheimer's disease (AD), the most common cause of dementia in the elderly, is
a progressive neurodegenerative disorder that gradually affects cognitive function and …

Design, Green Synthesis and in silico Studies of New Substituted Naphtho [1, 2‐e][1, 3] Oxazines as Potential Acetylcholinesterase Inhibitors

B Pouramiri, M Abbasi… - Chemistry & …, 2024 - Wiley Online Library
Alzheimer's disease (AD) is a prevalent neurodegenerative condition characterized by
progressive cognitive decline and memory impairment resulting from the degeneration and …

[PDF][PDF] Assessing a BN-doped graphene for the drug delivery of hydroxyurea anticancer

K Harismah, DK Sain, MF Al-Owaidi… - … Research in Applied …, 2023 - researchgate.net
A boron-nitrogen (BN)-doped graphene (G) was assessed in this work for approaching the
drug delivery of hydroxyurea (HU) anticancer. Density functional theory (DFT) calculations …

Synthesis and Evaluation of Acetylcholinesterase Inhibitory and Cytotoxic Activities of Pyrano[2,3-d]pyrimidines

NH Thanh, NTQ Giang, NV Ha… - Natural Product …, 2023 - journals.sagepub.com
Objective: The study was conducted to evaluate the in vitro acetylcholinesterase (AchE)
inhibition activity of novel pyrano [2, 3-d] pyrimidine derivatives. Methods: A series of new …

In vitro and in silico cholinesterase inhibitory potential of metabolites from Laurencia snackeyi (Weber-van Bosse) M. Masuda

K Palaniveloo, KH Ong, H Satriawan, S Abdul Razak… - 3 Biotech, 2023 - Springer
Alzheimer's disease (AD) is a neurodegenerative disease that causes deterioration in
intelligence and psychological activities. Yet, till today, no cure is available for AD. The …

[PDF][PDF] Investigating a Boron Nitride Plate for the Formaldehyde Adsorption: Density Functional Theory Calculations

K Harismah, MF Nassar, OT Hamid, MO AL-Khafaji… - 2022 - biointerfaceresearch.com
A boron nitride (BN) plate was investigated in this work for adsorbing the formaldehyde
(Frm) substance by performing the density functional theory (DFT) calculations. The singular …

Theoretical examination of molecular docking, pharmacokinetics and in-silico design of specific tacrine derivatives as anti-Alzheimer agents

IA Akinbo, A Ajala, MS Rufai, FI Baiwa… - Dutse Journal of Pure …, 2024 - ajol.info
A common neurological illness that affects many individuals globally is Alzheimer's disease
(AD). Its cause is currently unknown. One of the symptoms of AD is a reduction in cholinergic …

[PDF][PDF] Asian Journal of Green Chemistry

B Properties - Asian Journal of Green Chemistry, 2024 - sid.ir
More qualitative materials that are gotten from the combination of two or more materials of
less quality are termed as composite materials [1- 3]. Because of the persistence of plastic …