Both intratumoral regulatory T cell depletion and CTLA-4 antagonism are required for maximum efficacy of anti-CTLA-4 antibodies
Anti-CTLA-4 antibodies have successfully elicited durable tumor regression in the clinic;
however, long-term benefit is limited to a subset of patients for select cancer indications. The …
however, long-term benefit is limited to a subset of patients for select cancer indications. The …
Collagen Anchoring Agonist Antibodies for Cancer Immunotherapy
JR Palmeri - 2023 - dspace.mit.edu
While traditional cancer interventions such as surgery, radiation, and chemotherapy are
aimed at killing or removing the tumor cells themselves, immunotherapies instead seek to …
aimed at killing or removing the tumor cells themselves, immunotherapies instead seek to …