Purpose of review: Developing tailored immunosuppression regimens requires sensitive,
non-invasive tools for serial post-transplant surveillance as the current clinical standards …

The goal of this study was to evaluate the utility of urinary metabolomics for noninvasive
diagnosis of T cell–mediated rejection (TCMR) in pediatric kidney transplant recipients …

Background Subclinical and clinical T cell–mediated rejection (TCMR) has significant
prognostic implications in pediatric renal transplantation. The goal of this study was to …

Background. Urine CXCL10 (CXC motif chemokine ligand 10, interferon gamma-induced
protein 10 [IP10]) outperforms standard-of-care monitoring for detecting subclinical and early …

Background. Renal allograft injury secondary to subclinical and clinical tubulitis remains an
important cause of allograft fibrosis and loss despite modern immunosuppression. The goal …

Background. Injuries in kidney transplant is currently diagnosed by needle biopsy. A
noninvasive test that sensitively detects these injuries would benefit the patients. Methods …

Urine CXCL10 is a well characterized inflammation biomarker, which can be used to guide
performance of surveillance biopsies. Wide implementation into clinical practice depends on …

Background: There is an urgent need to develop and implement low cost, high-throughput
standardized methods for routine molecular assessment of transplant biopsies. Given the …

We investigated the clinical relevance of urinary cytokines/chemokines reflecting intrarenal
immunologic micromilieu as prognostic markers and the optimal measurement timing after …

Background Interferon-gamma inducible protein-10 (IP-10/CXCL10) is a chemokine
involved in the alloimmune response against kidney allograft. We aimed to investigate the …