The cardiovascular and other actions of angiotensin II (Ang II) are mediated by AT1 and AT2
receptors, which are seven transmembrane glycoproteins with 30% sequence similarity …

Angiotensinogen, the precursor molecule for angiotensins I, II and III, and the enzymes
renin, angiotensin-converting enzyme (ACE), and aminopeptidases A and N may all be …

The renin angiotensin system (RAS) produced hormone peptides regulate many vital body
functions. Dysfunctional signaling by receptors for RAS peptides leads to pathologic states …

Central infusion of angiotensin IV or its more stable analogues facilitates memory retention
and retrieval in normal animals and reverses amnesia induced by scopolamine or by …

Hippocampal lesions produce memory deficits, but the exact function of the hippocampus
remains obscure. Evidence is presented that its role in memory may be ancillary to …

Considerable evidence now suggests that the precursors and enzymes necessary for the
formation and degradation of biologically active forms of angiotensins are present in brain …

Recent studies from this laboratory have demonstrated that angiotensin II (Ang II) stimulates
the expression of plasminogen activator inhibitor 1 (PAI-1) in cultured endothelial cells. This …

In addition to its traditional role as a circulating hormone, angiotensin is also involved in
local functions through the activity of tissue renin-angiotensin systems that occur in many …

This review summarizes emerging evidence that supports the notion of a separate brain
renin-angiotensin system (RAS) complete with the necessary precursors and enzymes for …

The renin–angiotensin system (RAS) mediates several classic physiologies including body
water and electrolyte homeostasis, blood pressure, cyclicity of reproductive hormones and …