Th1/Th2 imbalance and heat shock protein mediated inflammatory damage triggered by manganese via activating NF-κB pathway in chicken nervous system in vivo …

Z Miao, K Zhang, R Bao, J Li, Y Tang… - Environmental Science and …, 2021 - Springer
Manganese (Mn) is a ubiquitous heavy metal pollutant in environment, and excess Mn can
damage nervous system of humans and animals. However, molecular mechanism of Mn …

Protective role of m6A binding protein YTHDC2 on CCNB2 in manganese-induced spermatogenesis dysfunction

Z Qi, Y Liu, H Yang, X Yang, H Wang, B Liu… - Chemico-biological …, 2022 - Elsevier
Human infertility has become the third largest serious disease in the world, seriously
affecting the quality of human fertility. Studies have shown that manganese (Mn) can …

Clozapine prevented social interaction deficits and reduced c-Fos immunoreactivity expression in several brain areas of rats exposed to acute restraint stress

RP de Oliveira, JS de Andrade, M Spina, JV Chamon… - PLoS …, 2022 - journals.plos.org
In the present study, we evaluate the effect of acute restraint stress (15 min) of male Wistar
rats on social interaction measurements and c-Fos immunoreactivity (c-Fos-ir) expression, a …

Exposure to manganese during sertoli cell formation and proliferation disturbs early testicular development in rats

AP Gomes-Silva, PC de Medeiros, LN Silva… - Reproductive …, 2023 - Elsevier
Manganese (Mn) is a metal and important micronutrient. However, exposure to
supraphysiological levels of Mn, which occur through fungicides, atmospheric emissions …

Gallic acid and omega‐3 fatty acids mitigate epididymal and testicular toxicity in manganese‐treated rats

SE Owumi, OF Danso, SO Nwozo - Andrologia, 2020 - Wiley Online Library
Environmental contamination by manganese is correlated with diverse health outcomes plus
reproductive dysfunction. Dietary gallic acid (GA) and omega‐3 fatty acids (ω‐3‐FA) are well …

[HTML][HTML] Reproductive toxicity assessment of Olusosun municipal landfill leachate in Mus musculus using abnormal sperm morphology and dominant lethal mutation …

OJ Ademola, CG Alimba, AA Bakare - … Analysis, Health and …, 2020 - ncbi.nlm.nih.gov
Mixture of xenobiotics in Olusosun landfill leachates (OSL) induced somatic and germ cell
genotoxicity in eukaryotic cells. However, whether the DNA-damaged germ cells can …

Neuroprotective effects of docosahexaenoic acid against sub-acute manganese intoxication induced dopaminergic and motor disorders in mice

R El Fari, A Abbaoui, A Bourziq, M Zroudi… - Journal of Chemical …, 2019 - Elsevier
Manganese (Mn) is an essential metallic trace element involved in several vital biological
functions. Conversely, exposure to excessive levels of Mn induces manganism, causing …

[HTML][HTML] Evaluation of testicular structure in mice after exposure to environmentally relevant doses of manganese during critical windows of development

TL Souza, AR Batschauer, PM Brito… - Ecotoxicology and …, 2021 - Elsevier
Despite being an essential trace element with great importance for vital metabolic activities,
the manganese (Mn) can also cause damage to organ systems. However, data on the effect …

Coridius chinensis Extract Promotes Leydig Cell Endocrine Function Rescuing Testosterone Deficiency and Sexual Behavior Insufficiency in Manganese‐Exposed …

N Luo, K Xiong, Y Wang, C Cen, Q Liu, F Wang… - Andrologia, 2024 - Wiley Online Library
Coridius chinensis is a traditional Chinese medicinal insect, whose extract (CcE) is widely
used for male reproductive disorders. Manganese (Mn2+) as a heavy metal pollutant can …

Evaluation of Mn exposure in the male reproductive system and its relationship with reproductive dysfunction in mice

TL Souza, AR Batschauer, PM Brito, J Leão-Buchir… - Toxicology, 2020 - Elsevier
Manganese (Mn) is essential for animal development and homeostasis. However,
anthropogenic activities increase the concentration of Mn in the environment and lead to …