Unveiling the Digital Evolution of Molecular Tumor Boards
Molecular tumor boards (MTB) are interdisciplinary conferences involving various experts
discussing patients with advanced tumors, to derive individualized treatment suggestions …
discussing patients with advanced tumors, to derive individualized treatment suggestions …
SeqCAT: Sequence Conversion and Analysis Toolbox
K Kornrumpf, NS Kurz, K Drofenik, L Krauß… - Nucleic Acids …, 2024 - academic.oup.com
Dealing with sequence coordinates in different formats and reference genomes is
challenging in genetic research. This complexity arises from the need to convert and …
challenging in genetic research. This complexity arises from the need to convert and …
Precise interpretation and prioritization of sequence variants with Onkopus for supporting molecular tumor boards
NS Kurz, K Kornrumpf, T Tucholski, K Drofenik, A König… - medRxiv, 2024 - medrxiv.org
One of the major challenges in precision medicine is the identification of pathogenic,
actionable variants and the selection of personalized treatments. We present Onkopus, a …
actionable variants and the selection of personalized treatments. We present Onkopus, a …
An evidence based reporting system for molecular tumorboards identifies novel therapeutics for t-cell lymphomas
N Schmidt, K Kornrumpf, L Ries, B Chapuy… - Blood, 2022 - ashpublications.org
Methods Utilizing newly developed bioinformatic methodology for molecular tumorboards 1,
2, genetic data from> 1800 patients with T-cell lymphomas (TCL) compiled from public …
2, genetic data from> 1800 patients with T-cell lymphomas (TCL) compiled from public …
Discovery of molecularly-informed therapeutic strategies for mature T-cell neoplasms
R Koch, N Schmidt, K Kornrumpf, L Ries, K Markus… - 2024 - researchsquare.com
Mature T-cell lymphomas and leukemias (mTCL) comprise a clinically and genetically
heterogeneous group of lymphoid malignancies. Most subtypes of peripheral T-cell …
heterogeneous group of lymphoid malignancies. Most subtypes of peripheral T-cell …
Exploring new treatment strategies for mature T-cell neoplasms based on genetic alterations
N Schmidt - 2024 - ediss.uni-goettingen.de
Mature T-cell leukemias and lymphomas (mTCL) comprise a heterogeneous group of
lymphoid malignancies that are generally associated with poor prognosis, low response to …
lymphoid malignancies that are generally associated with poor prognosis, low response to …