Abstract DICER1 syndrome (OMIM 606241, 601200) is a rare autosomal dominant familial
tumor predisposition disorder with a heterozygous DICER1 germline mutation. The most …

The tooth provides an excellent system for deciphering the molecular mechanisms of
organogenesis, and has thus been of longstanding interest to developmental and stem cell …

Abstract microRNAs (miRNAs) are important modulators of development. Owing to their
ability to simultaneously silence hundreds of target genes, they have key roles in large-scale …

Teeth are found in almost all vertebrates, and they therefore provide a general paradigm for
the study of epithelial organ development and evolution. Here, we review the developmental …

Teeth develop as ectodermal appendages from epithelial and mesenchymal tissues. Tooth
organogenesis is regulated by an intricate network of cell–cell signaling during all steps of …

The continuously growing mouse incisor serves as a valuable model to study stem cell
regulation during organ renewal. Epithelial stem cells are localized in the proximal end of …

Teeth are unique to vertebrates and have played a central role in their evolution. The
molecular pathways and morphogenetic processes involved in tooth development have …

The mouse incisor is a remarkable tooth that grows throughout the animal's lifetime. This
continuous renewal is fueled by adult epithelial stem cells that give rise to ameloblasts …

Dentin tissue is derived from mesenchymal cells induced into the odontoblast lineage. The
differentiation of odontoblasts is a complex process regulated by several transcriptional …

We report here identification and validation of the first papillomavirus encoded microRNAs
expressed in human cervical lesions and cell lines. We established small RNA libraries from …