[HTML][HTML] A double-edged sword: DLG5 in diseases
X Song, Q Li, J Zhang - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Abstract Discs large homolog 5 (DLG5), a key member of the membrane-associated
guanylate kinase (MAGUKs) family, is a scaffold molecule for signal transduction complexes …
guanylate kinase (MAGUKs) family, is a scaffold molecule for signal transduction complexes …
Alzheimer's disease as a major public health concern: Role of dietary saponins in mitigating neurodegenerative disorders and their underlying mechanisms
Saponins are triterpenoid or steroidal glycosides and are an important group of naturally
occurring compounds of plant origin. They exhibit diverse pharmacological potentials …
occurring compounds of plant origin. They exhibit diverse pharmacological potentials …
Green Synthesis of Silver Nanoparticles from Allium cepa L. Peel Extract, Their Antioxidant, Antipathogenic, and Anticholinesterase Activity
The present work deals with the green synthesis and characterization of silver nanoparticles
(AgNPs) using Allium cepa (yellowish peel) and the evaluation of its antimicrobial …
(AgNPs) using Allium cepa (yellowish peel) and the evaluation of its antimicrobial …
The role of machine learning and deep learning approaches for the detection of skin cancer
Machine learning (ML) can enhance a dermatologist's work, from diagnosis to customized
care. The development of ML algorithms in dermatology has been supported lately …
care. The development of ML algorithms in dermatology has been supported lately …
A Comprehensive In Silico Exploration of Pharmacological Properties, Bioactivities, Molecular Docking, and Anticancer Potential of Vieloplain F from Xylopia vielana …
Compounds derived from plants have several anticancer properties. In the current study,
one guaiane-type sesquiterpene dimer, vieloplain F, isolated from Xylopia vielana species …
one guaiane-type sesquiterpene dimer, vieloplain F, isolated from Xylopia vielana species …
Anti-Inflammatory, Analgesic and Antioxidant Potential of New (2S,3S)-2-(4-isopropylbenzyl)-2-methyl-4-nitro-3-phenylbutanals and Their Corresponding Carboxylic …
In the current study, a series of new (2 S, 3 S)-2-(4-isopropylbenzyl)-2-methyl-4-nitro-3-
phenylbutanals (FM1-6) with their corresponding carboxylic acid analogues (FM7-12) has …
phenylbutanals (FM1-6) with their corresponding carboxylic acid analogues (FM7-12) has …
Alkaloidal phytoconstituents for diabetes management: exploring the unrevealed potential
The main characteristic feature of diabetes mellitus is the disturbance of carbohydrate, lipid,
and protein metabolism, which results in insulin insufficiency and can also lead to insulin …
and protein metabolism, which results in insulin insufficiency and can also lead to insulin …
Anti-diabetic Activity of Brucine in Streptozotocin-Induced Rats: In Silico, In Vitro, and In Vivo Studies
Diabetes mellitus (DM) is a complex and multiple group of disorders, and understanding the
molecular mechanisms is a key role in identifying various markers involved in the diagnosis …
molecular mechanisms is a key role in identifying various markers involved in the diagnosis …
[HTML][HTML] Cardioprotective effect of 2-methoxy phenol derivatives against oxidative stress-induced vascular complications: an integrated in vitro, in silico, and in vivo …
Background Oxidative stress and inflammation play crucial roles in macro/microvascular
complications. Phenolic compounds and their derivatives show promise as therapeutic …
complications. Phenolic compounds and their derivatives show promise as therapeutic …
Synthesis, computational studies, antioxidant and anti-inflammatory bio-evaluation of 2, 5-disubstituted-1, 3, 4-oxadiazole derivatives
The 1, 3, 4-oxadiazole derivatives Ox-6a-f have been synthesized by incorporating
flurbiprofen moiety with the aim to explore the potential of target molecules to decrease the …
flurbiprofen moiety with the aim to explore the potential of target molecules to decrease the …