The aim of this International Menopause Society White Paper on premature ovarian
insufficiency (POI) is to provide the latest information regarding this distressing condition …

Mammalian eggs (oocytes) are formed during fetal life and establish associations with
somatic cells to form primordial follicles that create a store of germ cells (the primordial pool) …

The human ovary orchestrates sex hormone production and undergoes monthly structural
changes to release mature oocytes. The outer lining of the ovary (cortex) has a key role in …

Emerging studies indicate that the Hippo pathway, a highly conserved pathway that
regulates organ size control, plays an important role in governing ovarian physiology …

Compared to embryonic and induced pluripotent stem cells, mesenchymal stem/stromal
cells (MSCs) have made their presence felt with good therapeutic promise and safety profile …

Although advances in cancer treatment and early diagnosis have significantly improved
cancer survival rates, cancer therapies can cause serious side effects, including ovarian …

Fertility counseling should be offered to all individuals of young reproductive age early in the
patient's trajectory following a cancer diagnosis. Systemic cancer treatment and …

This text has been written as a practical guide, based on the author's experience over the
last 40 years of daily clinical practice and aiming to place the modern approach to the …

Many infertility specialists support the existence of a relationship between the levels of
mitochondrial DNA and the quality of the blastocysts. Despite the extensive use of pre …

Polycystic ovarian syndrome (PCOS) is a common global cause of anovulatory infertility but
underlying etiology leading to PCOS still remains elusive. Fetal and perinatal endocrine …