Kick-starting the zygotic genome: licensors, specifiers, and beyond
Zygotic genome activation (ZGA), the first transcription event following fertilization, kickstarts
the embryonic program that takes over the control of early development from the maternal …
the embryonic program that takes over the control of early development from the maternal …
[HTML][HTML] Genome folding and zygotic genome activation in mammalian preimplantation embryos
A Bondarieva, K Tachibana - Current Opinion in Genetics & Development, 2024 - Elsevier
The totipotent one-cell embryo, or zygote, gives rise to all germ layers and extraembryonic
tissues that culminate in the development of a new organism. A zygote is produced at …
tissues that culminate in the development of a new organism. A zygote is produced at …
Reconstitution of chromatin reorganization during mammalian oocyte development
J Wang, W Li, J Guo, X Xu, L Ge, B Li, C So - bioRxiv, 2024 - biorxiv.org
The final step of oocyte growth, which reorganizes chromatin from the uncondensed, non-
surrounded nucleolus (NSN) configuration to the condensed, surrounded nucleolus (SN) …
surrounded nucleolus (NSN) configuration to the condensed, surrounded nucleolus (SN) …