Chowing down: diet considerations in rodent models of metabolic disease
Diet plays a substantial role in the etiology, progression, and treatment of chronic disease
and is best considered as a multifaceted set of modifiable input variables with pleiotropic …
and is best considered as a multifaceted set of modifiable input variables with pleiotropic …
Islet health, hormone secretion, and insulin responsivity with low-carbohydrate feeding in diabetes
CAA Locatelli, EE Mulvihill - Metabolites, 2020 - mdpi.com
Exploring new avenues to control daily fluctuations in glycemia has been a central theme for
diabetes research since the Diabetes Control and Complications Trial (DCCT) …
diabetes research since the Diabetes Control and Complications Trial (DCCT) …
[HTML][HTML] Disentangling the effects of obesity and high-fat diet on glucose homeostasis using a photoperiod induced obesity model implicates ectopic fat deposition as a …
Objective Obesity in laboratory rodents is generally induced by feeding them a high fat diet
(HFD). This model does not permit separation of the impact of the HFD from the resultant …
(HFD). This model does not permit separation of the impact of the HFD from the resultant …
Increased variation in body weight and food intake is related to increased dietary fat but not increased carbohydrate or protein in mice
A variety of inbred mouse strains have been used for research in metabolic disorders.
Despite being inbred, they display large inter-individual variability for many traits like food …
Despite being inbred, they display large inter-individual variability for many traits like food …
Effects of dietary macronutrients on the hepatic transcriptome and serum metabolome in mice
Dietary macronutrient composition influences both hepatic function and aging. Previous
work suggested that longevity and hepatic gene expression levels were highly responsive to …
work suggested that longevity and hepatic gene expression levels were highly responsive to …
Impact of graded maternal dietary fat content on offspring susceptibility to high‐fat diet in mice
Objective Maternal high‐fat diet (HFD) increases offspring obesity, yet the impacts of
different levels of maternal dietary fat have seldom been addressed. In mice, the impact of …
different levels of maternal dietary fat have seldom been addressed. In mice, the impact of …
Unhealthy Diets Induce Distinct and Regional Effects on Intestinal Inflammatory Signalling Pathways and Long-Lasting Metabolic Dysfunction in Rats
The intestinal epithelium is a principal site for environmental agents' detection. Several
inflammation-and stress-related signalling pathways have been identified as key players in …
inflammation-and stress-related signalling pathways have been identified as key players in …