Inflammation is a complicated biological and pathophysiological cascade of responses to
infections and injuries, and inflammatory mechanisms are closely related to many diseases …

MicroRNAs (miRNAs, miRs) are short, endogenously initiated, non-coding RNAs that bind to
target mRNAs, leading to the degradation or translational suppression of respective mRNAs …

While immunosuppressive environments mediated by myeloid-derived suppressor cells
(MDSCs) have been well documented in glioma patients, the mechanisms of MDSC …

Abstract CD4+ T helper (TH) cells regulate appropriate cellular and humoral immune
responses to a wide range of pathogens and are central to the success of vaccines …

MicroRNAs (miRNAs) are small non-coding RNAs, 18–23 nucleotides long, which act as
post-transcriptional regulators of gene expression. miRNAs are strongly implicated in the …

Regulatory T cells (Tregs) prevail as a specialized cell lineage that has a central role in the
dominant control of immunological tolerance and maintenance of immune homeostasis …

Regulatory T cells (Tregs) prevent autoimmunity and tissue damage resulting from
excessive or unnecessary immune activation through their suppressive function. While their …

MicroRNAs are a class of evolutionarily conserved, short non-coding RNAs that post-
transcriptionally modulate the expression of multiple target genes. They are implicated in …

Abstract CD4+ CD25+ regulatory T cells (Tregs) are a class of CD4+ T cells with
immunosuppressive functions that play a critical role in maintaining immune homeostasis …

Aims The balance between various CD4+ T cell subsets through highly regulated
differentiation of naïve T cells is critical to ensure proper immune response, disruption of …