Going the extra (synaptic) mile: excitotoxicity as the road toward neurodegenerative diseases

A Armada-Moreira, JI Gomes, CC Pina… - Frontiers in cellular …, 2020 - frontiersin.org
Excitotoxicity is a phenomenon that describes the toxic actions of excitatory
neurotransmitters, primarily glutamate, where the exacerbated or prolonged activation of …

Glioma facilitates the epileptic and tumor-suppressive gene expressions in the surrounding region

K Komiyama, K Iijima, R Kawabata-Iwakawa… - Scientific Reports, 2022 - nature.com
Patients with glioma often demonstrate epilepsy. We previously found burst discharges in
the peritumoral area in patients with malignant brain tumors during biopsy. Therefore, we …

Hypocapnia attenuates local skin thermal perception to innocuous warm and cool stimuli in normothermic resting humans

T Fujimoto, K Dobashi, N Fujii… - American Journal …, 2023 - journals.physiology.org
When one is exposed to a stressful situation in their daily life, a common response is
hyperventilation. Although the physiological significance of stress-induced hyperventilation …

Genome-wide identification and characterization of novel long non-coding RNA in Ruminal tissue affected with sub-acute Ruminal acidosis from Holstein cattle

B Mahmoudi, J Fayazi, H Roshanfekr, M Sari… - Veterinary research …, 2020 - Springer
Sub-acute ruminal acidosis is a type of metabolic disorder in which affected cattle show a
considerable depression of rumen pH. This leads to a dramatic decline in productivity and …

Altered inhibition in the hippocampal neural networks after spreading depression

M Mesgari, N Ghaffarian, MK Ghadiri, H Sadeghian… - Neuroscience, 2015 - Elsevier
Prolonged neuronal depression after spreading depression (SD) is followed by a late
cellular and synaptic hyperexcitability. Intra-and extracellular recordings of bioelectrical …

[HTML][HTML] Possible roles of heteroreceptor complexes in excitotoxic processes

D Guidolin, C Tortorella, M Marcoli… - Exploration of …, 2024 - explorationpub.com
Excitotoxicity represents a neuropathological process, describing the toxic actions of
excitatory neurotransmitters, where the excessive or prolonged activation of glutamate …

碱中毒对小鼠皮质GABA 能神经元特性和编码能力的影响.

孙玲, 张忠玲, 常明秀, 方婧… - Progress in Modern …, 2016 - search.ebscohost.com
摘要目的: 研究碱中毒对小鼠皮质GABA 能神经元内在特性和编码能力的影响,
探讨碱中毒引起大脑功能障碍的机制. 方法: 选择17-22 天FVB-Tg 小鼠行脑片体外培养 …

Possibilities of pathogenetic correction of hyperkinetic disorders taking into account an acid-base balance

VN Hertsev, AN Stoyanov, TN Muratova… - Journal of Education …, 2019 - apcz.umk.pl
As a result of analysis of the available scientific data, a significant relationship between
hyperkinetic syndromes and changes in the acid-base state has been revealed. The …

Transcriptomic Alterations Related to Epilepsy and Tumor Suppression in the Peritumoral Area of a Rat Glioma Model

K Komiyama, K Iijima, R Kawabata-Iwakawa… - 2021 - researchsquare.com
Patients with glioma often demonstrate epilepsy. We previously found burst discharges in
the peritumoral area in patents with malignant brain tumors during biopsy. Therefore, we …

[引用][C] Transcriptomic alterations related to epilepsy and tumor suppression in the peritumoral area of a rat glioma model

込山和毅 - 2022 - Gunma University