In-cell NMR: Why and how?

FX Theillet, E Luchinat - Progress in Nuclear Magnetic Resonance …, 2022 - Elsevier
NMR spectroscopy has been applied to cells and tissues analysis since its beginnings, as
early as 1950. We have attempted to gather here in a didactic fashion the broad diversity of …

Responsive gadolinium (III) complex-based small molecule magnetic resonance imaging probes: Design, mechanism and application

Q Meng, M Wu, Z Shang, Z Zhang, R Zhang - Coordination Chemistry …, 2022 - Elsevier
Magnetic resonance imaging (MRI) is a molecular imaging technology that has been widely
adopted in biomedical and clinical diagnostics fields owing to its capability of deep tissue …

Activatable probes for diagnosis and biomarker detection by MRI

M Carril - Journal of Materials Chemistry B, 2017 - pubs.rsc.org
Magnetic resonance imaging (MRI) is a non-invasive imaging technique with widespread
use in diagnosis. Frequently, contrast in MRI is enhanced with the aid of a contrast agent …

Early detection and monitoring of cerebral ischemia using calcium-responsive MRI probes

T Savić, G Gambino, VS Bokharaie… - Proceedings of the …, 2019 - National Acad Sciences
Cerebral ischemia is one of the leading causes of mortality and disability in infants and
adults and its timely diagnosis is essential for an efficient treatment. We present a …

Supramolecular design based activatable magnetic resonance imaging

WC Geng, Z Zheng, DS Guo - View, 2021 - Wiley Online Library
Magnetic resonance imaging (MRI) has been widely used in clinical diagnosis. In recent
years, activatable MRI probes responding to specific changes in their microenvironment …

Endeavor toward Redox-Responsive Transition Metal Contrast Agents Based on the Cross-Bridge Cyclam Platform

R Uzal-Varela, A Rodríguez-Rodríguez, D Lalli… - Inorganic …, 2024 - ACS Publications
We present the synthesis and characterization of a series of Mn (III), Co (III), and Ni (II)
complexes with cross-bridge cyclam derivatives (CB-cyclam= 1, 4, 8, 11-tetraazabicyclo [6.6 …

19F Magnetic Resonance Imaging Signals from Peptide Amphiphile Nanostructures Are Strongly Affected by Their Shape

AT Preslar, F Tantakitti, K Park, S Zhang, SI Stupp… - ACS …, 2016 - ACS Publications
Magnetic resonance imaging (MRI) is a noninvasive imaging modality that provides
excellent spatial and temporal resolution. The most commonly used MR probes face …

Heading toward macromolecular and nanosized bioresponsive MRI probes for successful functional imaging

G Angelovski - Accounts of chemical research, 2017 - ACS Publications
Conspectus The quest for bioresponsive or smart contrast agents (SCAs) in molecular
imaging, in particular magnetic resonance imaging (MRI), is progressively increasing since …

Cell-permeable esterase-activated Ca (II)-sensitive MRI contrast agent

KW MacRenaris, Z Ma, RL Krueger… - Bioconjugate …, 2016 - ACS Publications
Calcium [Ca (II)] is a fundamental transducer of electrical activity in the central nervous
system (CNS). Influx of Ca (II) into the cytosol is responsible for action potential initiation and …

Ultrasmall nanoplatforms as calcium‐responsive contrast agents for magnetic resonance imaging

A Moussaron, S Vibhute, A Bianchi, S Gündüz, S Kotb… - Small, 2015 - Wiley Online Library
The preparation of ultrasmall and rigid platforms (USRPs) that are covalently coupled to
macrocycle‐based, calcium‐responsive/smart contrast agents (SCAs), and the initial in vitro …