Advances in viroid-host interactions
Viroids are small, single-stranded, circular RNAs infecting plants. Composed of only a few
hundred nucleotides and being unable to code for proteins, viroids represent the lowest …
hundred nucleotides and being unable to code for proteins, viroids represent the lowest …
Viroids and viroid-host interactions
Although they induce symptoms in plants similar to those accompanying virus infections,
viroids have unique structural, functional, and evolutionary characteristics. They are …
viroids have unique structural, functional, and evolutionary characteristics. They are …
RNA processing enables predictable programming of gene expression
Complex interactions among genetic components often result in variable systemic
performance in designed multigene systems,. Using the bacterial clustered regularly …
performance in designed multigene systems,. Using the bacterial clustered regularly …
Viroids: survivors from the RNA world?
R Flores, S Gago-Zachert, P Serra… - Annual review of …, 2014 - annualreviews.org
Because RNA can be a carrier of genetic information and a biocatalyst, there is a consensus
that it emerged before DNA and proteins, which eventually assumed these roles and …
that it emerged before DNA and proteins, which eventually assumed these roles and …
Novel ribozymes: discovery, catalytic mechanisms, and the quest to understand biological function
CE Weinberg, Z Weinberg… - Nucleic acids research, 2019 - academic.oup.com
Small endonucleolytic ribozymes promote the self-cleavage of their own phosphodiester
backbone at a specific linkage. The structures of and the reactions catalysed by members of …
backbone at a specific linkage. The structures of and the reactions catalysed by members of …
Rolling circle RNA synthesis catalyzed by RNA
RNA-catalyzed RNA replication is widely considered a key step in the emergence of life's
first genetic system. However, RNA replication can be impeded by the extraordinary stability …
first genetic system. However, RNA replication can be impeded by the extraordinary stability …
Homology-independent discovery of replicating pathogenic circular RNAs by deep sequencing and a new computational algorithm
Q Wu, Y Wang, M Cao, V Pantaleo… - Proceedings of the …, 2012 - National Acad Sciences
A common challenge in pathogen discovery by deep sequencing approaches is to
recognize viral or subviral pathogens in samples of diseased tissue that share no significant …
recognize viral or subviral pathogens in samples of diseased tissue that share no significant …
Novel viroid‐like RNAs naturally infect a filamentous fungus
K Dong, C Xu, I Kotta‐Loizou, J Jiang, R Lv… - Advanced …, 2023 - Wiley Online Library
To date, viroids have been found to naturally infect only plants, resulting in substantial
losses for some crops. Whether viroids or viroid‐like RNAs naturally infect non‐plant hosts …
losses for some crops. Whether viroids or viroid‐like RNAs naturally infect non‐plant hosts …
The fittest versus the flattest: experimental confirmation of the quasispecies effect with subviral pathogens
The “survival of the fittest” is the paradigm of Darwinian evolution in which the best-adapted
replicators are favored by natural selection. However, at high mutation rates, the fittest …
replicators are favored by natural selection. However, at high mutation rates, the fittest …
Viroids, the simplest RNA replicons: How they manipulate their hosts for being propagated and how their hosts react for containing the infection
The discovery of viroids about 45 years ago heralded a revolution in Biology: small RNAs
comprising around 350 nt were found to be able to replicate autonomously—and to incite …
comprising around 350 nt were found to be able to replicate autonomously—and to incite …