Pathophysiology and therapeutic approaches to acute decompensated heart failure

JN Njoroge, JR Teerlink - Circulation research, 2021 - Am Heart Assoc
Acute decompensated heart failure (ADHF) is one of the leading admission diagnoses
worldwide, yet it is an entity with incompletely understood pathophysiology and limited …

Natriuretic peptides

LB Daniels, AS Maisel - Journal of the American college of cardiology, 2007 - jacc.org
Natriuretic peptides (NPs) are released from the heart in response to pressure and volume
overload. B-type natriuretic peptide (BNP) and N-terminal-proBNP have become important …

BNP-guided vs symptom-guided heart failure therapy: the Trial of Intensified vs Standard Medical Therapy in Elderly Patients With Congestive Heart Failure (TIME …

M Pfisterer, P Buser, H Rickli, M Gutmann, P Erne… - Jama, 2009 - jamanetwork.com
Context It is uncertain whether intensified heart failure therapy guided by N-terminal brain
natriuretic peptide (BNP) is superior to symptom-guided therapy. Objective To compare 18 …

N-terminal–pro-brain natriuretic peptide predicts outcome after hospital discharge in heart failure patients

P Bettencourt, A Azevedo, J Pimenta, F Friões… - Circulation, 2004 - Am Heart Assoc
Background—Heart failure (HF) is responsible for a huge burden in hospital care. Our goal
was to evaluate the value of N-terminal–pro-brain natriuretic peptide (NT-proBNP) in …

How well does B-type natriuretic peptide predict death and cardiac events in patients with heart failure: systematic review

JA Doust, E Pietrzak, A Dobson, P Glasziou - Bmj, 2005 - bmj.com
Objective To assess how well B-type natriuretic peptide (BNP) predicts prognosis in patients
with heart failure. Design Systematic review of studies assessing BNP for prognosis in …

Statistical models and patient predictors of readmission for heart failure: a systematic review

JS Ross, GK Mulvey, B Stauffer, V Patlolla… - Archives of internal …, 2008 - jamanetwork.com
Background Readmission after heart failure (HF) hospitalization is an increasing focus for
physicians and policy makers, but statistical models are needed to assess patient risk and to …

Primary results of the Rapid Emergency Department Heart Failure Outpatient Trial (REDHOT) A multicenter study of B-type natriuretic peptide levels, emergency …

A Maisel, JE Hollander, D Guss, P McCullough… - Journal of the American …, 2004 - jacc.org
Objectives: The purpose of this study was to examine the relationships among B-type
natriuretic peptide (BNP) levels within the diagnostic range, perceived congestive heart …

BNP Consensus Panel 2004: A clinical approach for the diagnostic, prognostic, screening, treatment monitoring, and therapeutic roles of natriuretic peptides in …

MA Silver, A Maisel, CW Yancy… - Congestive heart …, 2004 - Wiley Online Library
Among the most exciting developments in the field of heart failure in recent times has been
the rediscovery of the natriuretic peptide system and its pleuripotent effects on cardiac …

Admission, discharge, or change in B-type natriuretic peptide and long-term outcomes: data from Organized Program to Initiate Lifesaving Treatment in Hospitalized …

RD Kociol, JR Horton, GC Fonarow… - Circulation: Heart …, 2011 - Am Heart Assoc
Background—B-type natriuretic peptide (BNP) has been associated with short-and long-
term postdischarge prognosis among hospitalized patients with heart failure. It is unknown if …

Natriuretic peptides in heart failure: atrial and B-type natriuretic peptides

AS Maisel, JM Duran, N Wettersten - Heart failure clinics, 2018 - heartfailure.theclinics.com
The natriuretic peptides (NPs) play a critical role in maintaining homeostasis in the
cardiovascular system, serving as counter-regulatory hormones for volume and pressure …