The role of non-invasive respiratory support (high-flow nasal oxygen and noninvasive
ventilation) in the management of acute hypoxemic respiratory failure and acute respiratory …

Mechanical ventilation may have adverse effects on both the lung and the diaphragm. Injury
to the lung is mediated by excessive mechanical stress and strain, whereas the diaphragm …

Mechanical ventilation can cause acute diaphragm atrophy and injury, and this is associated
with poor clinical outcomes. Although the importance and impact of lung-protective …

Respiratory drive, the intensity of the respiratory center's output, determines the effort
exerted in each breath. The increasing awareness of the adverse effects of both strong and …

Background During control mechanical ventilation (CMV), the driving pressure of the
respiratory system (Δ P rs) serves as a surrogate of transpulmonary driving pressure (Δ P …

Cardiac arrest (CA) is a major cause of morbidity and mortality frequently associated with
neurological and systemic involvement. Supportive therapeutic strategies such as …

The rise of model-based and machine learning methods have created increasingly realistic
opportunities to implement personalized, patient-specific mechanical ventilation (MV) in the …

Acute hypoxemic respiratory failure is the principal cause of hospitalization, invasive
mechanical ventilation and death in severe COVID-19 infection. Nearly half of intubated …

Abstract Background Flow Index, a numerical expression of the shape of the inspiratory flow-
time waveform recorded during pressure support ventilation, is associated with patient …

Background Venovenous extracorporeal membrane oxygenation (VV ECMO) is frequently
associated with deep sedation and neuromuscular blockades, that may lead to diaphragm …