Advanced liposome and polymersome-based drug delivery systems: Considerations for physicochemical properties, targeting strategies and stimuli-sensitive …
Liposomes and polymersomes are colloidal vesicles that are self-assembled from lipids and
amphiphilic polymers, respectively. Because of their ability to encapsulate both hydrophilic …
amphiphilic polymers, respectively. Because of their ability to encapsulate both hydrophilic …
Advances in SARS-CoV-2 receptor-binding domain-based COVID-19 vaccines
ABSTRACT Introduction The Coronavirus Disease 2019 (COVID-19) pandemic has caused
devastating human and economic costs. Vaccination is an important step in controlling the …
devastating human and economic costs. Vaccination is an important step in controlling the …
[HTML][HTML] Polymer-based nanosystems—A versatile delivery approach
AG Niculescu, AM Grumezescu - Materials, 2021 - mdpi.com
Polymer-based nanoparticles of tailored size, morphology, and surface properties have
attracted increasing attention as carriers for drugs, biomolecules, and genes. By protecting …
attracted increasing attention as carriers for drugs, biomolecules, and genes. By protecting …
Targeted polymersome delivery of a stapled peptide for drugging the tumor protein p53: BCL-2-family axis in diffuse large B-cell lymphoma
MR Schnorenberg, KM Hawley, AT Thomas-Toth… - ACS …, 2023 - ACS Publications
Diffuse large B-cell lymphoma (DLBCL) remains a formidable diagnosis in need of new
treatment paradigms. In this work, we elucidated an opportunity for therapeutic synergy in …
treatment paradigms. In this work, we elucidated an opportunity for therapeutic synergy in …
[HTML][HTML] Effect of SARS-CoV-2 mutations on the efficacy of antibody therapy and response to vaccines
SARS-CoV-2 causes severe acute respiratory syndrome, which has led to significant
morbidity and mortality around the world. Since its emergence, extensive prophylactic and …
morbidity and mortality around the world. Since its emergence, extensive prophylactic and …
[HTML][HTML] Detection of SARS-CoV-2 based on nucleic acid amplification tests (NAATs) and its integration into nanomedicine and microfluidic devices as point-of-care …
A Dorta-Gorrín, J Navas-Méndez… - International Journal of …, 2023 - mdpi.com
The coronavirus SARS-CoV-2 has highlighted the criticality of an accurate and rapid
diagnosis in order to contain the spread of the virus. Knowledge of the viral structure and its …
diagnosis in order to contain the spread of the virus. Knowledge of the viral structure and its …
Unleashing the potential of cell membrane-based nanoparticles for COVID-19 treatment and vaccination
Introduction: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a particular
coronavirus strain responsible for the coronavirus disease 2019 (COVID-19), accounting for …
coronavirus strain responsible for the coronavirus disease 2019 (COVID-19), accounting for …
[HTML][HTML] Polymersomes as a potential platform for cancer immunotherapy
JF Scheerstra, AC Wauters, J Tel… - Materials Today …, 2022 - Elsevier
With the focus in the field of cancer nanomedicine shifting from direct tumor targeting to
modulation of the immune system, new opportunities arise for the employment of …
modulation of the immune system, new opportunities arise for the employment of …
Adjuvant-protein conjugate vaccine with built-in TLR7 agonist on S1 induces potent immunity against SARS-CoV-2 and variants of concern
RY Zhang, SH Zhou, CB He, J Wang… - ACS Infectious …, 2022 - ACS Publications
With the global pandemic of the new coronavirus disease (COVID-19), a safe, effective, and
affordable mass-produced vaccine remains the current focus of research. Herein, we …
affordable mass-produced vaccine remains the current focus of research. Herein, we …
Shaping neonatal immunization by tuning the delivery of synergistic adjuvants via nanocarriers
Adjuvanted nanocarrier-based vaccines hold substantial potential for applications in novel
early-life immunization strategies. Here, via mouse and human age-specific in vitro …
early-life immunization strategies. Here, via mouse and human age-specific in vitro …