Progress in understanding the role of lncRNA in programmed cell death

N Jiang, X Zhang, X Gu, X Li, L Shang - Cell death discovery, 2021 - nature.com
Long non-coding RNAs (lncRNAs) are transcripts longer than 200 nucleotides but not
translated into proteins. LncRNAs regulate gene expressions at multiple levels, such as …

Exploring the Role of Staphylococcus aureus in Inflammatory Diseases

H Chen, J Zhang, Y He, Z Lv, Z Liang, J Chen, P Li… - Toxins, 2022 - mdpi.com
Staphylococcus aureus is a very common Gram-positive bacterium, and S. aureus infections
play an extremely important role in a variety of diseases. This paper describes the types of …

A decade of cell death studies: Breathing new life into necroptosis

I Khan, A Yousif, M Chesnokov, L Hong… - Pharmacology & …, 2021 - Elsevier
Programmed cell death (PCD) has been a major area of constantly growing interest over the
last three decades. Originally, apoptosis was considered the only mechanistic pathway for …

Location, location, location: A compartmentalized view of TNF-induced necroptotic signaling

AL Samson, SE Garnish, JM Hildebrand… - Science signaling, 2021 - science.org
Necroptosis is a lytic, proinflammatory cell death pathway, which has been implicated in host
defense and, when dysregulated, the pathology of many human diseases. The central …

Crosstalk between lncRNAs in the apoptotic pathway and therapeutic targets in cancer

N Ebrahimi, S Parkhideh, S Samizade… - Cytokine & growth factor …, 2022 - Elsevier
The assertion that a significant portion of the mammalian genome has not been translated
and that non-coding RNA accounts for over half of polyadenylate RNA have received much …

Dysregulated microbiota-driven gasdermin D activation promotes colitis development by mediating IL-18 release

H Gao, M Cao, Y Yao, W Hu, H Sun, Y Zhang… - Frontiers in …, 2021 - frontiersin.org
The balance between gut microbiota and host is critical for maintaining host health. Although
dysregulation of the gut microbiota triggers the development of various inflammatory …

[HTML][HTML] A novel role for necroptosis in the pathogenesis of necrotizing enterocolitis

AD Werts, WB Fulton, MR Ladd, A Saad-Eldin… - Cellular and molecular …, 2020 - Elsevier
Background & Aims Necrotizing enterocolitis (NEC) is a devastating disease of premature
infants characterized by Toll-like receptor 4 (TLR4)-dependent intestinal inflammation and …

[HTML][HTML] Macrophage scavenger receptor 1 mediates lipid-induced inflammation in non-alcoholic fatty liver disease

O Govaere, SK Petersen, N Martinez-Lopez… - Journal of …, 2022 - Elsevier
Background & Aims Obesity-associated inflammation is a key player in the pathogenesis of
non-alcoholic fatty liver disease (NAFLD). However, the role of macrophage scavenger …

Comprehensive analysis of mitochondrial dysfunction and necroptosis in intracranial aneurysms from the perspective of predictive, preventative, and personalized …

B Chen, K Xie, J Zhang, L Yang, H Zhou, L Zhang… - Apoptosis, 2023 - Springer
Mitochondrial dysfunction and necroptosis are closely associated, and play vital roles in the
medical strategy of multiple cardiovascular diseases. However, their implications in …

The regulation of necroptosis and perspectives for the development of new drugs preventing ischemic/reperfusion of cardiac injury

LN Maslov, SV Popov, NV Naryzhnaya… - Apoptosis, 2022 - Springer
In the last 10 years, mortality from acute myocardial infarction (AMI) has not significantly
decreased. This situation is associated with the absence in clinical practice of highly …