Fungal morphology: a challenge in bioprocess engineering industries for product development
HA El Enshasy - Current Opinion in Chemical Engineering, 2022 - Elsevier
Fungal biofactories are well established in bioprocess industries. They have been used for
the production of essential biomolecules in chemical, food, and pharmaceutical industries …
the production of essential biomolecules in chemical, food, and pharmaceutical industries …
Something old, something new: challenges and developments in Aspergillus niger biotechnology
The filamentous ascomycete fungus Aspergillus niger is a prolific secretor of organic acids,
proteins, enzymes and secondary metabolites. Throughout the last century, biotechnologists …
proteins, enzymes and secondary metabolites. Throughout the last century, biotechnologists …
Understanding and controlling filamentous growth of fungal cell factories: novel tools and opportunities for targeted morphology engineering
Filamentous fungal cell factories are efficient producers of platform chemicals, proteins,
enzymes and natural products. Stirred-tank bioreactors up to a scale of several hundred m³ …
enzymes and natural products. Stirred-tank bioreactors up to a scale of several hundred m³ …
Cellular organization in lab-evolved and extant multicellular species obeys a maximum entropy law
The prevalence of multicellular organisms is due in part to their ability to form complex
structures. How cells pack in these structures is a fundamental biophysical issue, underlying …
structures. How cells pack in these structures is a fundamental biophysical issue, underlying …
Synchrotron radiation‐based microcomputed tomography for three‐dimensional growth analysis of Aspergillus niger pellets
H Müller, C Deffur, S Schmideder… - Biotechnology and …, 2023 - Wiley Online Library
Filamentous fungi produce a wide range of relevant biotechnological compounds. The close
relationship between fungal morphology and productivity has led to a variety of analytical …
relationship between fungal morphology and productivity has led to a variety of analytical …
From spores to fungal pellets: A new high‐throughput image analysis highlights the structural development of Aspergillus niger
H Müller, L Barthel, S Schmideder… - Biotechnology and …, 2022 - Wiley Online Library
Many filamentous fungi are exploited as cell factories in biotechnology. Cultivated under
industrially relevant submerged conditions, filamentous fungi can adopt different …
industrially relevant submerged conditions, filamentous fungi can adopt different …
Low pressure gas transfer in fibrous media with progressive infiltration: correlation between different transfer modes
C Charles, C Descamps, GL Vignoles - … Journal of Heat and Mass Transfer, 2022 - Elsevier
Permeation of gases in fibrous preforms of C/C composites has been studied with various
degrees of infiltration, between 60% and 12% pore volume fraction, both experimentally with …
degrees of infiltration, between 60% and 12% pore volume fraction, both experimentally with …
3D imaging and analysis to unveil the impact of microparticles on the pellet morphology of filamentous fungi
A Dinius, H Müller, D Kellhammer… - Biotechnology and …, 2024 - Wiley Online Library
Controlling the morphology of filamentous fungi is crucial to improve the performance of
fungal bioprocesses. Microparticle‐enhanced cultivation (MPEC) increases productivity …
fungal bioprocesses. Microparticle‐enhanced cultivation (MPEC) increases productivity …
Varied solutions to multicellularity: The biophysical and evolutionary consequences of diverse intercellular bonds
The diversity of multicellular organisms is, in large part, due to the fact that multicellularity
has independently evolved many times. Nonetheless, multicellular organisms all share a …
has independently evolved many times. Nonetheless, multicellular organisms all share a …
Regression modelling of conditional morphogene expression links and quantifies the impact of growth rate, fitness and macromorphology with protein secretion in …
TC Cairns, T de Kanter, XZ Zheng, P Zheng… - … for Biofuels and …, 2023 - Springer
Background Filamentous fungi are used as industrial cell factories to produce a diverse
portfolio of proteins, organic acids, and secondary metabolites in submerged fermentation …
portfolio of proteins, organic acids, and secondary metabolites in submerged fermentation …