[HTML][HTML] Basics of antibody phage display technology

L Ledsgaard, M Kilstrup, A Karatt-Vellatt, J McCafferty… - Toxins, 2018 - mdpi.com
Antibody discovery has become increasingly important in almost all areas of modern
medicine. Different antibody discovery approaches exist, but one that has gained increasing …

Evolution of phage display libraries for therapeutic antibody discovery

Y Zhang - MAbs, 2023 - Taylor & Francis
Monoclonal antibodies (mAbs) and their derivatives have emerged as one of the most
important classes of biotherapeutics in recent decades. The success of mAb is due to their …

Functionalized terpolymer-brush-based biointerface with improved antifouling properties for ultra-sensitive direct detection of virus in crude clinical samples

M Forinová, A Pilipenco, I Visova… - … applied materials & …, 2021 - ACS Publications
New analytical techniques that overcome major drawbacks of current routinely used viral
infection diagnosis methods, ie, the long analysis time and laboriousness of real-time …

[HTML][HTML] Antibody 27F3 broadly targets influenza A group 1 and 2 hemagglutinins through a further variation in VH1-69 antibody orientation on the HA stem

S Lang, J Xie, X Zhu, NC Wu, RA Lerner, IA Wilson - Cell reports, 2017 - cell.com
Antibodies that target both group 1 and group 2 influenza A viruses are valuable for
therapeutic and vaccine development, but only a few have been reported to date. Here, we …

Bacteriophages: Status quo and emerging trends toward one health approach

R Samson, M Dharne, K Khairnar - Science of The Total Environment, 2023 - Elsevier
The alarming rise in antimicrobial resistance (AMR) among the drug-resistant pathogens
has been attributed to the ESKAPEE group (Enterococcus faecium, Staphylococcus aureus …

[HTML][HTML] Antibody CDR amino acids underlying the functionality of antibody repertoires in recognizing diverse protein antigens

HP Peng, HJ Hsu, CM Yu, FH Hung, CP Tung… - Scientific Reports, 2022 - nature.com
Antibodies recognize protein antigens with exquisite specificity in a complex aqueous
environment, where interfacial waters are an integral part of the antibody–protein complex …

[HTML][HTML] Antibody cross-reactivity in antivenom research

L Ledsgaard, TP Jenkins, K Davidsen, KE Krause… - Toxins, 2018 - mdpi.com
Antivenom cross-reactivity has been investigated for decades to determine which
antivenoms can be used to treat snakebite envenomings from different snake species …

Unmasking stem-specific neutralizing epitopes by abolishing N-linked glycosylation sites of influenza virus hemagglutinin proteins for vaccine design

WC Liu, JT Jan, YJ Huang, TH Chen, SC Wu - Journal of virology, 2016 - Am Soc Microbiol
Influenza virus hemagglutinin (HA) protein consists of two components, ie, a globular head
region and a stem region that are folded within six disulfide bonds, plus several N-linked …

[HTML][HTML] Eradicating mesothelin-positive human gastric and pancreatic tumors in xenograft models with optimized anti-mesothelin antibody–drug conjugates from …

HJ Hsu, CP Tung, CM Yu, CY Chen, HS Chen… - Scientific Reports, 2021 - nature.com
Mesothelin (MSLN) is an attractive candidate of targeted therapy for several cancers, and
hence there are increasing needs to develop MSLN-targeting strategies for cancer …

[PDF][PDF] Leveraging monoclonal antibodies as therapeutics to address antimicrobial resistance in bacteria

V Verma - Journal of Applied Biology and Biotechnology, 2023 - researchgate.net
Over the past two decades, several technologies have become available to rapidly develop
therapeutic monoclonal antibodies (MAbs) against any target of interest. Consequently …