[HTML][HTML] Basics of antibody phage display technology
L Ledsgaard, M Kilstrup, A Karatt-Vellatt, J McCafferty… - Toxins, 2018 - mdpi.com
Antibody discovery has become increasingly important in almost all areas of modern
medicine. Different antibody discovery approaches exist, but one that has gained increasing …
medicine. Different antibody discovery approaches exist, but one that has gained increasing …
Evolution of phage display libraries for therapeutic antibody discovery
Y Zhang - MAbs, 2023 - Taylor & Francis
Monoclonal antibodies (mAbs) and their derivatives have emerged as one of the most
important classes of biotherapeutics in recent decades. The success of mAb is due to their …
important classes of biotherapeutics in recent decades. The success of mAb is due to their …
Functionalized terpolymer-brush-based biointerface with improved antifouling properties for ultra-sensitive direct detection of virus in crude clinical samples
M Forinová, A Pilipenco, I Visova… - … applied materials & …, 2021 - ACS Publications
New analytical techniques that overcome major drawbacks of current routinely used viral
infection diagnosis methods, ie, the long analysis time and laboriousness of real-time …
infection diagnosis methods, ie, the long analysis time and laboriousness of real-time …
[HTML][HTML] Antibody 27F3 broadly targets influenza A group 1 and 2 hemagglutinins through a further variation in VH1-69 antibody orientation on the HA stem
Antibodies that target both group 1 and group 2 influenza A viruses are valuable for
therapeutic and vaccine development, but only a few have been reported to date. Here, we …
therapeutic and vaccine development, but only a few have been reported to date. Here, we …
Bacteriophages: Status quo and emerging trends toward one health approach
The alarming rise in antimicrobial resistance (AMR) among the drug-resistant pathogens
has been attributed to the ESKAPEE group (Enterococcus faecium, Staphylococcus aureus …
has been attributed to the ESKAPEE group (Enterococcus faecium, Staphylococcus aureus …
[HTML][HTML] Antibody CDR amino acids underlying the functionality of antibody repertoires in recognizing diverse protein antigens
Antibodies recognize protein antigens with exquisite specificity in a complex aqueous
environment, where interfacial waters are an integral part of the antibody–protein complex …
environment, where interfacial waters are an integral part of the antibody–protein complex …
[HTML][HTML] Antibody cross-reactivity in antivenom research
L Ledsgaard, TP Jenkins, K Davidsen, KE Krause… - Toxins, 2018 - mdpi.com
Antivenom cross-reactivity has been investigated for decades to determine which
antivenoms can be used to treat snakebite envenomings from different snake species …
antivenoms can be used to treat snakebite envenomings from different snake species …
Unmasking stem-specific neutralizing epitopes by abolishing N-linked glycosylation sites of influenza virus hemagglutinin proteins for vaccine design
WC Liu, JT Jan, YJ Huang, TH Chen, SC Wu - Journal of virology, 2016 - Am Soc Microbiol
Influenza virus hemagglutinin (HA) protein consists of two components, ie, a globular head
region and a stem region that are folded within six disulfide bonds, plus several N-linked …
region and a stem region that are folded within six disulfide bonds, plus several N-linked …
[HTML][HTML] Eradicating mesothelin-positive human gastric and pancreatic tumors in xenograft models with optimized anti-mesothelin antibody–drug conjugates from …
Mesothelin (MSLN) is an attractive candidate of targeted therapy for several cancers, and
hence there are increasing needs to develop MSLN-targeting strategies for cancer …
hence there are increasing needs to develop MSLN-targeting strategies for cancer …
[PDF][PDF] Leveraging monoclonal antibodies as therapeutics to address antimicrobial resistance in bacteria
V Verma - Journal of Applied Biology and Biotechnology, 2023 - researchgate.net
Over the past two decades, several technologies have become available to rapidly develop
therapeutic monoclonal antibodies (MAbs) against any target of interest. Consequently …
therapeutic monoclonal antibodies (MAbs) against any target of interest. Consequently …