Use of supersaturable formulations has been demonstrated as an effective approach to
improve solubility and oral absorption of poorly water-soluble compounds. In supersaturable …

Objectives Supersaturating formulations hold great promise for delivery of poorly soluble
active pharmaceutical ingredients (APIs). To profit from supersaturating formulations …

Self-emulsifying drug delivery systems (SEDDSs) are a vital strategy to enhance the
bioavailability (BA) of formulations of poorly water-soluble compounds. However, these …

At present, the majority of APIs synthesized today remain challenging tasks for formulation
development. Many technologies are being utilized or explored for enhancing solubility …

Synthesis, characterization and assessment of therapeutic efficacy of chitosan-
ricobendazole complex were carried out for the first time in this work. Study of physico …

The ultimate aim of this study was to develop asulacrine (ASL)-loaded long-circulating
liposomes to prevent phlebitis during intravenous (iv) infusion for chemotherapy. Poly …

Rectal drug administration could offer advantages in the delivery of medicines for children
by avoiding swallowability issues, improving stability and enabling administration by …

This study is the first to investigate and demonstrate the potential of microemulsions (MEs)
for sustained release parenteral drug delivery, due to phase transition behavior in aqueous …

The goal of elimination of the human filariases would benefit greatly from the use of a
macrofilaricidal agent. In vivo trials in humans and many experimental animal models …

Triclabendazole is the first-line drug of choice to treat and control fasciolasis, a neglected
parasitic human disease. It is a class II/IV compound according to the Biopharmaceutics …