determination and the implementation of preventive, diagnostic or therapeutic medical
strategies. However, the ESC Guidelines do not override in any way whatsoever the …

The function of the right ventricle determines the fate of patients with pulmonary
hypertension. Since right heart failure is the consequence of increased afterload, a full …

In pulmonary hypertension, the right ventricle adapts to the increasing vascular load by
enhancing contractility (“coupling”) to maintain flow. Ventriculoarterial coupling implies that …

Pulmonary arterial hypertension (PAH) is a rare dyspnoea-fatigue syndrome caused by a
progressive increase in pulmonary vascular resistance and eventual right ventricular (RV) …

The task of developing ESC Guidelines covers not only the integration of the most recent
research, but also the creation of educational tools and implementation programmes for the …

Objectives: The purpose of this study was to examine the relationship between changes in
pulmonary vascular resistance (PVR) and right ventricular ejection fraction (RVEF) and …

Frank's Windkessel model described the hemodynamics of the arterial system in terms of
resistance and compliance. It explained aortic pressure decay in diastole, but fell short in …

Pulmonary hypertension (PH) due to left heart disease, classified as group 2 according to
the Dana Point 2008 classification, is believed to be the most common cause of PH and is …

Mathematical models of the human heart are evolving to become a cornerstone of precision
medicine and support clinical decision making by providing a powerful tool to understand …

Pulmonary embolism (PE) is the leading cause of in-hospital death and the third most
frequent cause of cardiovascular death. The clinical presentation of PE is variable, and …