A major rise in the prevalence and impact of Alzheimer's disease (AD) is projected in the
coming decades, resulting from increasing life expectancy, thus leading to substantially …

Modeling and predicting biological dynamic systems and simultaneously estimating the
kinetic structural and functional parameters are extremely important in systems and …

Given the fact that our biological existence is rooted in a complex system within our cells
with thousands of interactions among genes and metabolites, research community in …

Colorectal cancer (CRC) is one of the most commonly diagnosed cancers and a major
cause of cancer death. However, the molecular mechanisms underlying CRC initiation …

The genomic era continues to revolutionize our understanding of the evolution of
biodiversity. In phycology, emphasis remains on assembling nuclear and organellar …

DEsubs is a network-based systems biology R package that extracts disease-perturbed
subpathways within a pathway network as recorded by RNA-seq experiments. It contains an …

In the era of network medicine, pathway analysis methods play a central role in the
prediction of phenotype from high throughput experiments. In this paper, we present a …

Background Towards discovering robust cancer biomarkers, it is imperative to unravel the
cellular heterogeneity of patient samples and comprehend the interactions between cancer …

Accurate predictions of classification biomarkers and disease status are indispensable for
clinical cancer diagnosis and research. However, the robustness of conventional gene …

This work offers a guided walkthrough of one of the most promising research areas in
modern life sciences, enabling a deeper understanding of involved concepts and …