Anti‐vascular endothelial growth factor for neovascular age‐related macular degeneration

SD Solomon, K Lindsley, SS Vedula… - Cochrane Database …, 2014 - cochranelibrary.com
Background Age‐related macular degeneration (AMD) is the most common cause of
uncorrectable severe vision loss in people aged 55 years and older in the developed world …

Introduction: understanding the role of angiogenesis and antiangiogenic agents in age-related macular degeneration

SB Bressler - Ophthalmology, 2009 - Elsevier
Inhibition of angiogenesis is critical in the prevention and treatment of neovascular age-
related macular degeneration (AMD). Pathologic states such as hypoxia, ischemia, or …

A treat and extend regimen using ranibizumab for neovascular age-related macular degeneration: clinical and economic impact

OP Gupta, G Shienbaum, AH Patel, C Fecarotta… - Ophthalmology, 2010 - Elsevier
PURPOSE: To evaluate the visual outcome, number of injections, and direct medical cost of
a “treat and extend” regimen (TER) in managing neovascular age-related macular …

Anti-VEGF agents in the treatment of neovascular age-related macular degeneration: applying clinical trial results to the treatment of everyday patients

DM Brown, CD Regillo - American journal of ophthalmology, 2007 - Elsevier
PURPOSE: The vision gains reported with monthly intravitreal ranibizumab in the MARINA
and ANCHOR trials led to an immediate paradigm shift in the treatment of neovascular AMD …

A systematic review of the adverse events of intravitreal anti-vascular endothelial growth factor injections

MI Van der Reis, EC La Heij, Y De Jong-Hesse… - Retina, 2011 - journals.lww.com
Background: Intravitreal ranibizumab and pegaptanib are registered for neovascular age-
related macular degeneration. No formal safety study has been conducted for intravitreal …

Association of complement factor H and LOC387715 genotypes with response of exudative age-related macular degeneration to intravitreal bevacizumab

MA Brantley Jr, AM Fang, JM King, A Tewari… - Ophthalmology, 2007 - Elsevier
PURPOSE: To investigate whether there is an association between complement factor H
(CFH) or LOC387715 genotypes with response to treatment with intravitreal bevacizumab …

Assessment of artifacts and reproducibility across spectral-and time-domain optical coherence tomography devices

J Ho, AC Sull, LN Vuong, Y Chen, J Liu, JG Fujimoto… - Ophthalmology, 2009 - Elsevier
PURPOSE: To report the frequency of optical coherence tomography (OCT) scan artifacts
and to compare macular thickness measurements, interscan reproducibility, and interdevice …

Incidence of acute onset endophthalmitis following intravitreal bevacizumab (Avastin) injection

JO MASON III, MF White, RM Feist, ML Thomley… - Retina, 2008 - journals.lww.com
Purpose: To report the incidence of acute endophthalmitis as a complication of intravitreal
bevacizumab (Avastin)(IVB) injection in a tertiary vitreoretinal group practice. Methods: A …

Pharmacotherapy for neovascular age-related macular degeneration: an analysis of the 100% 2008 medicare fee-for-service part B claims file

RJ Brechner, PJ Rosenfeld, JD Babish… - American journal of …, 2011 - Elsevier
PURPOSE: To describe the usage patterns of pharmacological treatments for neovascular
age-related macular degeneration (AMD) in Medicare fee-for-service beneficiaries. DESIGN …

Bevacizumab (Avastin) for the treatment of ocular disease

JB Gunther, MM Altaweel - Survey of ophthalmology, 2009 - Elsevier
The use of intravitreal bevacizumab (Avastin) has greatly expanded since its introduction
into ophthalmic care 3 years ago. A PubMed search on 1 August 2008 revealed 51 ocular …